In Dark Matters, Fringe star John Noble explores the most fascinating and unusual real-life scientific research ever conducted. Using reenactments and CGI, the show explores the moments of scientific history where individuals went to extreme measures to achieve a breakthrough; from head transplantations and actual zombie investigations, to human and ape cross-breeds. These stories are as outlandish as a great sci-fi script, or as disturbing as a classic horror tale; the only difference is that they’re all true. John Noble is the perfect tour guide to escort viewers through this sordid world of research gone horribly wrong, but in some cases, led us to the technology and science that we enjoy today.