Matt is summoned to help an old friend, Ab Butler, who has been shot in the back and left for dead. However, Matt faces a difficult situation when Ab's partner shows up and tells his side of the story.

German immigrant and town blacksmith, Emil Wolhter and his German mail order bride, Gretchen Mueller, are to be married. Matt, Doc and Chester along with Emil meet Gretchen at the stage station. Emil and Gretchen throw a big wedding party for all their friends in Dodge;however, not everyone in Dodge is friendly to Emil and Gretchen. Town troublemaker Tolman has it in for Emil because Tolman thinks that Emil cheated him in a blacksmith deal. Tolman and his gang scheme up a plan to get Emil Wolhter out of his house. While Emil is out of his house one evening, Tolman and his gang of troublemakers burn Emil's house to the ground. When Matt offers to help Emil find the men who did this, Emil rejects Matt's offer and pursues these men by himself. Emil administers his own brand of justice to the men.

Matt arrests Finn Pickett after recognizing his face from a wanted poster. On the way back to Dodge, Pickett's vengeful sons try to free their father as Matt and Chester face a water shortage.

Martin Nagel is a hard working store owner that has plans to build up his business and eventually leave the business to his son, Lee Nagel. When Martin Nagel is killed in a freak accident, Lee Nagel thinks that his Uncle (Hutch) did the killing. Lee is highly suspicious of his Uncle Hutch and attempts to convince Marshall Dillon that his Uncle killed his Father to claim the family business.

While Matt and Chester are transporting a prisoner on a stage coach to Wichita, Matt learns that the stage is also carrying gold. Matt fears that outlaws might attack the stage for the gold. While at a stagecoach stopover, the outlaws attack the station. Matt, Chester, the stagecoach driver along with a traveling preacher and a young woman, attempt to fight off the outlaws the best they can.

Matt is called in to deal with a corrupt sheriff in Tascosa.

Matt's old friend, Esteban Garcia, tracks a man into Dodge and plans to kill him for stealing his wife.

A buffalo hunter (Spadden) and his partner Ritchie come to Dodge City causing trouble. Spadden has the reputation for bullying other people and bullying his buffalo skinner, Ritchie. When Jim Cornet's friend is killed in a fight by Spadden, Spadden and Cornet have angry words. Later that evening, Matt and Chester discover Jim Cornet's body lying dead in an alley. They also discover Cornet lying drunk in the alley just a few feet away from Jim Cornet's body. Since Matt and Cornet had been arguing earlier, Matt thinks that Spadden might have murdered Cornet. Spadden is tried for murder, but the Judge is of the opinion that there is just not enough evidence to convict Spadden. Spadden is acquitted from the charge of murder. Matt thinks that there are some unusual circumstances in this case and launches an investigation. Matt discovers Ritchie's body in the stable. Spadden admits he beat Ritchie to death. As the investigation unfolds, Matt finally gets to the true facts of who killed Jim

Matt is taken prisoner by a madman named Rack and his simpleton partner, Augie. Matt's only hope is to turn Augie against Rack.

A young army drummer named Raffie is terrorized by two bullying mule skinners.

Jake Creed accuses his young hired hand, Ben Tolliver, of horse theft.

The vicious Dolan brothers move in on a tough cattle rancher and his non-violent son.

Gus Mather comes into Dodge and throws a big wake for a man named Orson Boggs Doc and Chester are suspicious of this whole wake situation, but Chester and Doc attend the wake nonetheless and partake of the free drinks. When Matt comes back to Dodge from his business trip, Chester informs Matt on what has been going on . Matt also thinks something strange is going on as well. Matt and Chester are so suspicious of Gus Mather's story about Orson Boggs, they decide to do an investigation on all of this. While Matt and Chester are doing an investigation, they run into a man on the prairie. He tells them that he knows of a Orson Boggs, but has never heard of Gus Mather. He tells Matt that Orson Boggs lived in the Red Bank area of the prairie. Matt and Chester find Orson Bogg's farm. They discover Bogg's wife at the farm. Mrs. Boggs tells Matt that her husband is certainly not dead and that this story that Gus Mather is telling in Dodge about Orson being dead is false. Mrs Boggs come to Dodge

A young drifter takes a job as cook at Delmonico's but accidentally kills a crazy buffalo hunter who complains about his cooking.

A scheming woman (Else Hedgepath), who is after the money and wealth of Hannibal Bass, makes a play for Hannibal, but runs into some serious, SERIOUS trouble though when she tangles with *MRS* Bass!

When 2 outlaws shoot and kill a storekeeper and his young employee, Matt sets out on to the prairie to find the killers. When one of the killers (Red Lime) dies from a gunshot wound from Marshall Dillon's gun, the other outlaw (Joe Lime) vows revenge on Matt Dillon for killing his Brother When Matt returns back to Dodge without the men and with a fever, Doc gives Matt something to help him rest and fight the fever. While Matt is resting, Chester cleans Matt's gun. Chester removes all of the bullets from the chambers, but before Chester can put the bullets back into Matt's gun, Chester gets a message that Doc wants to see Chester in the Doctor's office While Chester is up in Doc's office, the other killer rides back into Dodge wanting revenge for Matt killing his Brother. He tells Carl the stable man that he plans to kill Matt. Carl the stable man tells Miss Kitty that the outlaw Joe Lime was now in Dodge and is gunning for Matt. Miss Kitty awakens Matt from a state of fever to warn

Rough and rowdy Minnie comes to Dodge Cith and sets her designs on Doc Adams much to the delight of Matt, Chester and Kitty. Trouble comes though when Minnie's husband comes to Dodge and finds out that his Minnie is sweet on Doc.