Documentary in which Louis Theroux visits Fresno in California's Central Valley to take a look at how crystal meth addiction is affecting the local community. As he infiltrates the town, he experiences the reality of meth abuse, with addicts inviting him into their homes to see them take hit after hit of their favourite drug. He talks to the local police and meets a couple who have sustained their marriage despite a 25-year meth addiction and losing custody of their five children. He also witnesses arrests of families doing meth together, and sees the work being done to combat the destruction caused by the drug.