Once again Ash sets his sights on a new region and a new adventure. Continuing his journey alone, Ash arrives in the beautiful Unova region with just Pikachu at this side. While on his way to visit Professor Juniper, Unova's resident professor, a mysterious shadow appears above and Pikachu loses the ability to use his electric attacks. Ash also encounters a trainer named Trip and the two decide to have an unlikely ending battle.

With Pikachu healed up, Ash decides to not return with his mom and Professor Oak to Kanto and to travel around the Unova region instead. As he begins his travels he meets a girl named Iris and together they decide to travel with each other, but when Pikachu and Axew are stolen by Team Rocket, will they be able to save their only Pokémon?

After learning that the first gym of Unova is located in Striaton City, Ash and Iris begin their journey there. However, they are stopped by a boy who requests their help. A group of Sandile are terrorizing his sand bath resort and he wants Ash and Iris's help to stop them.

While on the way to Striaton City, Ash and Iris arrive in Karakusa Town and Ash hears about a place called the Pokémon Battle Club. Interested, he decides to go check it out. However, trouble is abound as a mysterious pokémon has been spotted nearby and both Ash and Iris wants to capture it.

Ash and Iris arrive in Striaton City, the location of Unova's first gym. When they arrive in town they meet a boy named Cilan who says he is a Pokémon Sommelier, someone who is able to test the compatibility between a Pokémon and trainer. He leads them to the Gym where it is revealed that he and his two brothers are all the Gym Leaders of Striaton City. Will Ash be able to defeat the three brothers and win his first badge?

Ash is taking a break at the Pokémon Center following his Gym Battle when all of a sudden Iris comes dashing in. Apparently Axew has fallen asleep and will not wake up. Overhearing, a professor named Fennel and her Munna come to help them.

While on the way to the next Gym, Ash, Iris, and Cilan stop to take a break. While eating a Snivy comes by and starts eating their food. They try to stop it but it uses Attract to stun Pikachu and cause other mischief. What will they do to stop it.

While stopping for lunch by a river, Pikachu and Axew's food suddenly goes missing. Everyone begins to search around and they find a Darumaka eating the food. They give chase but lose it and get lost.

On the way to Nacrene City, Axew wanders off to get some apples and ends up trapped in the horms of the bug pokémon Scolipede. The Pokémon begins rampaging and now everyone must find a way to stop it and get Axew back.

On the way to the next city Ash and his friends run into Trip again. Determined to prove that his previous loss was just a fluke, Ash challenges him to a battle. Trip accepts and the two get ready to have a five-on-five battle.

On the way to Nacrene City, Ash and friends encounter the Pokémon Dwebble. However, this Dwebble does not have a rock on its back as it should. It begins to make a new shell, but then three more Dwebble show up and trouble starts.

Ash and friends are continuing their journey when a group of kids suddenly appear in front of them. They begin throwing mud balls at Ash and his friends and as they run off, a Trubbish steals Ash's hat. They then give chase.

Ash and friends meet a girl named Bianca. Professor Juniper has asked Bianca to meet up with them in order to deliver a badge case to Ash. As Bianca gets the case out it is all dusty from sitting at the bottom of her bag. Suddenly a Minccino comes by and snatches the case and runs off with it. Ash and friends give chase.

Ash, Iris, and Cilan finally arrive at Nacrene City, the location of Unova's second gym. When they arrive at the gym, which is located in the city's museum, the door is locked. They soon find out that some strange things have been happening in the museum. Ash, determined to have his gym battle, decides to head inside and find out what is happening.

With their museum adventure behind them, Ash finally gets to challenge the Nacrene City Gym Leader, Lenora. Lenora specializes in Normal-type Pokémon and is no pushover. Will Ash be able to defeat Lenora and earn his second badge?

After his devastating loss against Lenora, Ash heads to the Nacrene City Battle Club to train for a rematch. While at the Battle Club, his training proves useful for both Oshawott and Tepig. With renewed confidence, Ash heads back to the gym to battle Lenora yet again. Will he defeat Lenora and win his second badge?

The day everyone has been waiting for has arrived! Ash's egg finally hatches, and it hatches into a Scraggy! However, the celebration ends when Scraggy proves to be a little troublemaker, and soon puts Ash and friends in danger with some wild Pokémon.

Continuing their journey, Ash and friends reach Pinwheel Forest. There Ash sets his sights on catching a Sewaddle after encountering one. However, this Sewaddle is not careful and winds up in some dangerous situations. Meanwhile, Ash and friends also receive help with Sewaddle from Castelia City Gym Leader Burgh.

Continuing their journey, Ash and friends come across an authorized Pokémon Connoisseurer. The Connoisseurer is at a new store performing readings for people and their Pokémon. They decide to go watch them so that Ash can get a free reading and Cilan can see another Connoisseurer in action. However, this Connoisseurer has a connection to Cilan.

While Ash is doing some training with his Scraggy, he and his friends are confronted by the same Sandile they met near Nuvema Town. Ash, wanting to accept Sandile's challenge is interrupted by three Ducklett which quickly snatch Ash's hat and Sandile's sunglasses.

Ash, Iris, and Cilan arrive at the famous Skyarrow Bridge, their last obstacle before reaching Castelia City. They try crossing the bridge, but a Gothitelle appears and prevents them from crossing. They must now find a way to get past it and get into the city.

Ash and friends have finally arrived in Castelia City. While exploring the city they run into Burgh. After hearing a noise underground, they go to find out what it was and find a wild Venipede. It is injured, and even though they heal it, the other Venipede in the sewers become upset and begin attacking the city above. Now Ash and friends must help to stop them.

The time has arrived, Ash is finally going to battle Burgh to try and win his third badge in Unova. Burgh is an excellent Bug-type trainer with many tricks up his sleeve. Will Ash be able to win his third badge?

Ash, Iris, Cilan and Bianca are on their way to Nimbasa City. Axew encounters an Emolga that had just stolen a bunch of apples from a group of Patrat.

Iris decides to do some training with her new Emolga. However, while training it is discovered that it has a problem. Whenever Emolga uses Volt Switch, instead of switching places with one of Iris's other Pokémon, it also switches places with Ash and Cilan's Pokémon as well!

Continuing to Nimbasa City, Ash and friends suddenly find themselves caught in the rain. They notice a mansion nearby and go inside hoping to seek shelter from the rain. However, things are not as they seem. Soon a group of Litwick begin tormenting them and cause havoc.

While on the way to Nimbassa City, Ash and friends encounter a trainer who is skilled in training Dragon-type Pokémon. Iris, determined to achieve her goal given to her by the elder of her town, seeks the wisdom of the trainer, hoping to make Axew stronger.

On the way to Nimbasa City, Ash meets a Pokémon trainer and the two decide to battle. During the battle Oshawott's scalchop is kicked away from Oshawott and becomes lost in the woods. Devastated, Oshawott frantically searches for it, and eventually a replacement for it.

While on the way to Nimbasa City, Ash and friend encounter a group of Cottonee. One of these Cottonee is in love with another one, but she rejects him, so Cilan decides to help the Pokémon win her love.

Continuing their journey to Nimbasa City, Ash and friends are suddenly woken up in the middle of the night by a mysterious light. Soon after they encounter a professor and the mysterious Pokémon Elgyem.

Continuing their journey to Nimbasa City, Ash and friends stop to have lunch. However, they end up ruining Cilan's lunch. Soon after Ash and Iris wander off and run into Trip. After seeing Trip's new Pokémon Ash is eager to battle and Trip agrees to a three one three battle. Who will win?

While taking a break on their journey, Ash and friends come under attack by wild Pokémon and the gang's Pokemon are badly poisoned. The only thing nearby that can heal them are herbs found at the bottom of a nearby lake. However, when Oshawott goes to get them, it is attacked by a wild Palpitoad and Stunfisk. Now everyone must find a way to stop the two Pokémon and heal the gang's Pokemon.

On their way to Nimbasa City, a girl confronts Iris and demands a battle against her and Axew. She says she is a Dragon Buster and it is her job to defeat Dragon Trainers. Due to his lack of experience Axew falls easily and in a fit of rage, Iris calls out Excadrill. Excadrill still ignores Iris and too is defeated. Following the battle Iris finally reveals what happened to her and Excadrill and decides it is time to finally get him to listen to her.

On their way to Nimbasa City, Ash and friends come across a group of Roggenrola who are being targeted by Team Rocket. When Team Rocket reveals their plan for the Pokémon they decide to stop them and save the Pokémon.

Ash and friends arrive in a town where the pokémon Audino is popular among the residents. However, the Audino have been mysteriously disappearing and acting strangely. Cilan decides to help Officer Jenny get to the bottom of this strange case.

Ash, Iris, and Cilan meet up with Professor Juniper and Fennel who reveal they are going to revive a Pokémon fossil. the fossil is the pokémon Archen. Archen is a wild pokémon that likes to do as it pleases, but it cannot fly. Ash and friend decide to help it learn to fly. Meanwhile, Team Rocket also set their sites on the pokémon.

Continuing to Nimbasa City, Ash and the gang decide to take a rest stop in a town. They run into Bianca who presents a fishing competition poster, unknowingly staged by Team Rocket. Cilan decides to enter the fishing contest. Meanwhile Team Rocket plans to steal the Pokemon the contestants caught.

Continuing to Nimbasa City, Ash and friend encounter a boy who directs movies. The boy is having troubles with both his lead actress and his pokémon Zorua. Ash and friends agree to help him with his movie.

Ash and friends arrive in Nimbasa Town where they learn of a tournament that is to be held. They decide to enter it before they leave town. However, they have stiff competition as trainers they've encountered in Unova also gather for the tournament.

The next round of the Club Battle tournament begins with a battle between Cilan and Trip. Meanwhile, Ash, Iris, and Bianca wait in the wings for their upcoming battles. Who will progress to the next round?

The Club Battle tournament continues with Ash and Georgia's battle ending. Next up is Cilan vs Luke and Iris vs Stephan. With tough opponents ahead of them will Cilan and Iris continue to advance in the tournament?

The Club Battle semi-finals conclude with Ash and Iris as the victors. Now the two friends are set to go head to head in the tournament finale. Who will be crowned the victor?

On the way to Nimbasa City, Ash and friends find Meowth of Team Rocket lying in a bush. Meowth says he botched a Team Rocket operation and was fired and disowned. He then joins Ash, Iris, and Cilan. Meanwhile a Scrafty comes by and kidnaps Axew.

While continuing to Nimbasa City, Ash and friends come across a Purrloin. Meowth and Oshawott fall for the little pokémon and soon begin to follow whatever it says. However, Cilan doesn't trust Purrloin and follows everyone reluctantly.

On the way to Nimbasa City, Ash and friends encounter a Beheeyem. After discovering it's secret ability, they decide to try and test it out. Meanwhile, Officer Jenny shows up and reveals that she is investigating the Beheeyem.

While on the way to Nimbasa City, Ash and friends come across a Cubchoo that has been separated from its pack. They decide to help find the pack, but that proves difficult when another group of Beartic constantly attacks them.

Ash and friend finally arrive in Nimbasa City. Before heading to gym they decide to check out the Battle Subway. However, a mysterious event causes the Subway System to halt. They head to the Pokmon Center where strange events begin...

Back in Nimbasa City following the subway disaster, Ash and friends encounter Bianca again. She is also there to battle Elesa at the gym. However, the battle is put on hold temporarily while Elesa is modeling. After seeing Bianca and Ash, Elesa returns to the gym. Bianca's match is stopped briefly by the appearance of her father. Her father wants her to return home, saying she is not ready to be a trainer. However, Elesa manages to convince him to let her battle. Bianca's dad agrees to let her continue traveling if she can defeat Elesa.

Ash finally gets his chance to battle Elesa for his fourth Unova Gym badge. Ash is confident in his line-up and believes the battle will be no problem. As expected, Elesa's Zebstrika takes center stage first. Using his trusted Palpitoad, Ash manages to take down the Pokémon that single-handedly took out all of Bianca's Pokémon. However, when Elesa defeats Palpitoad Ash is left rethinking his entire battle strategy.

Following Ash's victory at the Nimbasa Gym, Ash, Iris, and Cilan decide to do some sight seeing in Nimbasa City. However, Cilan quickly becomes distracted by a stamp rally. If one can collect all the stamps, they will get a chance to battle the Subway Bosses, Ingo and Emmet. While collecting the stamps, Cilan meets Erina who has lost her Axew. Cilan decides to help her find it. Meanwhile, Ash and Iris find Erina's Axew and try to find her owner.

Ash and friends begin their journey towards Driftveil City. On their way they run into Trip. Their reunion is short lived as everyone is surprised when the Champion of Unova, Alder appears! Trip, having met Alder when he was younger, wants to show Alder his progress as a trainer. However, Ash challenges him to a battle. During the battle Alder gives no commands to his Bouffalant, and falls asleep. This causes Trip to loose interest in Alder as a champion, though when a wild Gigalith begins rampaging, his view of him might change.

Continuing to Driftveil City, Ash and friends come across a trainer named Toby who is training his three Maractus for a Pokémon musical. However, one of his Maractus keeps messing up at a certain part of the routine, messing the whole routine up. When Toby starts to give up hope on his routine, Ash, Iris, and Cilan decide to help him and his Maractus learn the routine.

On the way to Driftveil City, Ash and friends stop at a Pokémon Center where they meet a Pokémon Photographer named Robert. Robert shows them his photographs and everyone is impressed. Robert then shows them his grandfather's photobook. Iris and Cilan are shocked at one of the pictures. The pictures shows all four seasonal forms of Sawsbuck together in one place. Believing this to be impossible, they question Robert and he says he wants to try and find the place the picture was taken and prove that the picture is real. Ash, Iris, and Cilan, wanting to see the Sawsbuck as well, join Robert on his journey.

Continuing their way to Driftveil City, Ash and Iris have a practice battle with Scraggy and Axew. After the battle, a Gothita appears and takes a liking to Scraggy. Gothita's trainer Katharine appears soon after. After seeing how much Gothita likes Scraggy, she offers Ash a trade. Ash refuses to trade Scraggy, and so Katharine demands a battle, and if she wins he must trade Scraggy. Midway through the battle it starts to rain and everyone runs to a nearby cottage to take shelter. During the middle of the night Gothita wakes up and takes off with Scraggy. Axew and Snivy give chase but will they be able to stop Gothita?

Continuing their journey to Driftveil City, Ash and Cilan are about to have a practice battle. However, two Deino run into the area and start wrecking all their stuff and running out of control. Ash and Iris decide to capture them, but it fails. Soon a man named Bobby comes by and reveals that he is watching these Deino for other trainers at his Daycare Center. They follow him back to his Daycare Center and see all the Pokémon he is taking care of. They also see that there is a third Deino at the center, but it is very shy. As Ash and Cilan help Bobby take care of the other pokémon, Iris makes it her personal mission to help the shy Deino come out of its shell.

Ash and friends arrive in Driftveil City and immediately head to the gym. However, the gym leader, Clay, does not want to battle at the moment. With nothing else to do they decide to tour the city. They run into a motorcyclist named Charles who acts like their tour guide. Soon they witness a crime taking place and the town's hero, the Mighty Accelgaurd, save them. Ash becomes a fan of the hero and wants to meet him, which leads them to being in the middle of a villainous plot.

While in Driftveil City, Ash and friends run into Cilan's brother Chili. Chili has also left the Striaton Gym so he can improve as a trainer. He and Cilan have a battle which ends with Cilan's victory. Following the battle Chili and Pansear blame each other for the loss and the two end up in a fight. Pansear takes off leading to everyone searching for it. Meanwhile, Pansear is determined to become stronger and prove itself.

Ash tries to challenge Clay to a gym battle again but Clay refuses because he has to find some Revival Herbs for Driftviel City. He says if Ash can find some, he will battle him. Ash, Iris, and Cilan learn that they grow on Milos Island and head there to find some. Upon arriving on the island they find out that the herbs have all dried up for some reason. They meet Lewis who decides to pray to Landorus in order to save the island. However, things go unexpectedly wrong when the Legendary Weather pokémon Tornadus and Thundurus show up and begin rampaging.

Ash and friends have succeeded in summoning Landorus.Team Rocket alert Dr. Zager of this and he begins his journey to the island. Despite the legend saying Landorus is key to the battle being stopped, Landorus begins to become overwhelmed by the combined forces of Tornadus and Thundurus. Before Ash and friends can figure out what to do, Dr. Zager arrives and captures the Kami trio. Everyone must now figure out how to save the trio and restore Milos Island.

After returning to Driftveil City with a bunch of Revival Herbs, Clay finally accepts Ash's gym challenge. Clay's first Pokémon is Krokorok, who quickly proves Clay and his Ground-Type pokémon are all about power. Ash must overcome Clay's powerful and tactful attacks if he wishes to earn his fifth badge.

After winning his fifth badge, Ash and friends begin heading for Mistralton City. On the way they notice a Joltik has taken all of Pikachu, Emolga, and Stunfisk's electric energy, leaving them severely weak. Upon healing them at the Pokémon center they run into Bianca who had the battery in her Xtransceiver drained as well. Nurse Joy determines that something must have happened in Chargestone Cave to make the Joltik and Galvantula appear in the forest. Bianca, who was already heading for the cave to see Professor Juniper, joins the group as they try to figure out what is happening at the cave.

Ash and friends have joined Professor Juniper at Chargestone Cave so that Juniper and Bianca can trade their Karrablast and Shelmet so they may evolve. Before the trade they decide to have a battle. However, the battle is soon interrupted by a strange electric disturbance in one of the caves areas. After investigating and discovering and helping an injured Klinklang, they return to base camp and proceed with the trade. However, Bianca's new Escavalier wont' listen to Bianca. Professor Juniper decides they should have a tag battle with Ash and Cilan to get Bianca and Escavalier in sync.

Professor Juniper's father Cedric arrives at Chargestone Cave where he reveals that he is trying to find some ruins nearby that are said to be related to the Hero's Legend and Zekrom. Ash, Iris, and Cilan are eager to see the ruins as well as ask Cedric if they can join him. He agrees and they all set out for the ruins. Once they get there they get more than they bargained for when they stumble upon trap after trap on their way to ruins secret treasure.

While on the way to Mistralton City, the Sunglasses Krokorok appears and demands to battle with Pikachu. However, the resulting battle sends both Pokémon flying. Ash, Iris, and Cilan manage to track them down to a nearby town where they find Pikachu with a kid name Mick. Mick and his friends Glenn and Sean like to battle but Glenn never lets Mick battle since he has no strong Pokémon. Mick asks Ash if he can borrow Pikachu and battle his friends and Ash agrees. Ash then begins to train with Mick so he can battle properly.

While on the way to Mistralton City, the group stops to have lunch. However, a heard of Bouffalant stampedes towards them and causes Iris, Axew, Snivy, Tepig, and Oshawott to get get separated from everyone else. While trying to find Ash and Cilan Iris runs into Nurse Joy who explains that the Bouffalant and very territorial and will attack anyone who is not a Bouffalant. In order to find each other and get out of the area everyone must now wear disguises to avoid being attacked.

Ash, Iris, and Cilan finally arrive in Mistralton City. Upon arriving they head to the gym where they find out they need a reservation to challenge the Gym Leader. Ash makes a reservation just as Skyla, the Gym Leader, arrives via plane. When she exits she announces the Gym battles will take place with 15 challengers. Ash and Cilan are horrified to see Skyla's own method of battling called "Air Battles". Using her Air Battles method, Skyla mentally determines whether or not a trainer could defeat her or not. As a Gym Leader himself, Cilan decides to put an end to the Air Battles and challenges Skyla to a regular battle.

Ash and Skyla's grandfather convince Skyla to have a battle with Ash so that Skyla can see her Air Battles might not always be right. Despite having no concrete plan, Ash is determined that his team of Krokorok, Tranquill, and Pikachu ccan take down Skyla and prove Air Battles are not the way to go. The next day the battle begins. However, Skyla quickly takes out Krokorok putting Ash behind early in the battle. Will Ash be able to win, earn his sixth Unova Badge, and prove Air Battles are wrong?

After winning his sixth badge, Ash and friends bump into Stephan. He is in town to compete in the Bell of Wishes Festival that is being held that day. Ash,Iris, and Cilan, after finding out that the winner gets to ring the bell atop Mistralton Tower and get a wish granted, decide to compete in the festival.

Ash, Iris, Cilan, and Stephan arrive in a town where a new tournament called the Clubsplosion is to be held. They are all excited to enter the tournament and soon reunite with Bianca, Trip, Burgundy, and Georgia who are all also entering. As the tournament gets underway, who will make it past the first round?

The Clubsplosion tournament continues to rage on with Iris and Burgundy being the next battle. Although Burgundy's Dewott has an advantage over Iris's Excadrill, Iris and Excadrill, are able tosuccessful get past that and pull off a win. The next battle sees Georgia battling with her newly evolved Bisharp. As the round is set to conclude, the final battle is Trip vs. Bianca. Who will come out victorious.

The Clubsplosion tournament continues to heat up as Trip and Bianca continue their battle. It's a battle of the titans as Trip's newly evolved Conkeldurr goes up against Bianca's newly evolved Emboar. Surprising to everyone, Bianca defeats Trip and advances to the next round, where she must now face Georgia in battle. Meanwhile, Ash and Cilan begin their next round battles.

The Clubsplosion tournament is drawing to close. As the semi finals progress, Ash and Bianca are both defeated, leaving Stephan as one of the two finalists. As a battle of the fighting types begins, will Stephan be able to win the competition?

While journeying to Icirrus City, Ash and friends are put in danger when Axew is kidnapped by a wild Durant. They must now go deep into Durant's nest in order to get Axew back.

Ash, Iris, and Cilan become lost in Twist Mountain and stumble upon an archeologist. He is looking for the fossil of the ancient pokémon Tirtouga. However, Team Rocket is also looking for the fossil.

Team launch their plan to revive the Tirtouga fossil and use it to open the Gate of Time.

On the way to Iccirus City, Ash and friends run into a trainer who turns out to be Tepig's previous trainer who abandoned him. The trainer wants to battle Ash and prove Tepig is useless.

Ash and friends run into Brycen, the Gym Leader of Iccirus City. They then join him to help stop a poacher from catching a Volcarona.

Ash challenges Brycen in order to try and win his seventh Unova Gym Badge.

Ash and friends come across a young girl who is trying to choose her first Pokémon. Cilan then competes with another Connoisseur to help the young girl.

Ash and friends run into Gerogia who in on her way to a Ferroseed Research in order to try and make her pokémon more powerful. However, once they get there they are thrown into a major crisis and electric moss begins growing uncontrollably.

Ash, Iris and Cilan arrive in Virbank City for Ash's next Gym Badge. They meet Luke and his Zorua who are in Virbank City for the opening of Pokéstar Studios and Cilan ends up dragging Ash and Iris to the studios. The group meet Mr. Gold, the owner of the studios and complements Luke on his previous film and wish him luck in the upcoming film competition. Luke asks Ash and his friends for help in the competition and they agree to help him.

Ash is preparing for his battle at the Virbank Gym at the Pokecenter where he sees many trainers enter with poisoned pokemon. He learns that the gym leader of the Virbank Gym specializes in Poison-type pokemon and should come up with a strategy to avoid poisonous attacks. The gym leader, Roxie suggests that Ash should use six pokemon in his battle while she uses three pokemon.

Ash’s battle against Roxie continues after her Koffing knocks out Ash’s Boldore and Unfezant. Koffing is then knocked out by Ash’s Leavanny and then Roxie sends out her Scolipede.