It's an all-new Oprah with two of Hollywood's favorite leading men. George Clooney and Matt Damon talk about Ocean's Twelve! Who wouldn't want to spend an hour with these guys?

Amy Fisher (1992: had an affair with Joey Buttafuoco when she was minor and Joey above 40) releases the real story and tells she just wants to go on with her life

Tiffany, Mattie, Ryan...follow up with some of the most unforgettable children we've ever met!

Miracle moments captured on tape. A starving girl who put a face on famine...did she survive? Then, baby girls abandoned, abused, and left to die-Lisa Ling investigates. And don't miss it-Oprah's Book Club meets again!

(Marge Schott, owner, Cincinnall Reds; Mary Kay Ash, Mary Kay Cosmetics; Suzanne de Passe, president, Motown Productions; Debbie Fields, Mrs. Fields Cookies; Barbara Proctor, president, Proctor Gardner Advertising)

One of the guests Oprah followed up on was Trista Rehn's mother, Roseanne, who was in the audience when Trista appeared on Oprah March 17, 2003. Roseanne Rehn mentioned in Oprah After the Show that she was waiting for the Senior Bachelorette version of "The Bachelorette." Oprah ran with it and presented eight men as candidates for dates with Roseanne. Trista interviewed the eight men and narrowed the selection to three, giving them roses. These three will take Roseanne on dates over the next week or two. Roseanne received a makeover courtesy of Oprah. Trista confirmed that the wedding to Ryan Sutter is still on, but no date has yet been set.

Mega-stars join our dream team: so cool Gwen Stefani and her rock star romance, heartthrob Enrique Iglesias, and super teen star Hilary Duff! Their fans never saw it coming!

Oprah's waited 51 years to do this…don't miss it! Then, learn how to look 10 years younger right now! Plus, she had let herself go, like so many others. How these people turned back the clock and look younger.

Now, this is reality TV! The world's largest tumor and a medical miracle that left Oprah speechless! Then, an update on the bone-chilling fall that was seen around the world. Plus, a plane plummets...could anyone walk away? Extreme video that will shock you.

This is a first and it is big! Ladies he is all yours...Ashton Kutcher is here...on marriage, babies and the love of his life, Demi Moore! Then, meet the other woman in his life. Plus, funnyman Bernie Mac!

For the second year in a row, Oscar® opens his doors for Oprah with a historic broadcast from the Kodak Theatre! The best dressed, the big winners, behind the scenes-our cameras are everywhere! Plus, an exclusive first interview with Oscar® host Chris Rock!

She said her baby stopped breathing and her daughter had cancer…but this mother of two made it all up. Now she is here to tell the truth…or is she? Her former friends don't buy it. A pathological liar confesses.

Are you ready, New York and L.A.? Oprah's Wildest Dreams Bus is coming to you! Big stars are making dreams come true. Josh Groban, Mariah Carey, and an emotional return-Nate Berkus is back, doing what he loves. Plus, it has been 10 years in the making! Only one person could help Oprah bring this dream to life-Halle Berry! The Wildest Dreams Bus strikes again.

Scott Peterson's own sister believed he was innocent. Now, she says he is a cold-blooded killer, and has 33 reasons why she is convinced her brother is guilty. The only family member to speak out against him, she opens up about her recent trip to prison to see him, Scott's bizarre behavior and what he said about Amber. His marriage, his mother, his sex life…new details you haven't heard.

Dumped! Thrown out! She hits rock-bottom…and then finds the man of her dreams. Love, betrayal, romance: Kimberly Elise, Tyler Perry and Shemar Moore in the movie people are "buzzing" about!

Britney talks about Justin Timberlake, Crossroads, her VMA performance, her foundation and many other things as well as sings "I'm a Slave 4 U" and "I'm Not a Girl, Not Yet a Woman".