Blossom (Mayim Bialik), who is the only girl in the house live with her two brothers Anthony (Michael Stoyanov) and Joey (Joey Lawrence) and her father Nick (Ted Wass). Blossom likes to hang-out and do things with Six (Jenna Von Oy) her best friend. Theme Song: "My Opinionation" by Mike Post and Steve Geyer.
As Blossom records a video diary entry, she hears her parents arguing. Then they tell Blossom they have an appointment with the family lawyer. Blossom daydreams about what will happen when her parents divorce, but they return home happily and tell her they were just updating their wills.
Blossom reaches puberty, and substitutes an older friend for her absentee mother to talk about it.
Blossom looks forward to her first prom date, with Joey's friend Bobby, but after Joey warns him about Bobby's reputation as a ladies' man, Nick forbids her to go out with him.
Blossom can't stand her dad's new girlfriend.
Nick leaves Blossom in charge of home one night while he performs on a cruise ship, and her imagination kicks into high gear when she sees Anthony's new girlfriend Stephanie stealing a family heirloom but is afraid to tell him for fear he will be driven back to drugs.
Nick is disturbed by Blossom's increasing interest in sex, while after sneaking off to a make-out party with Six and two boys, guilty Blossom dreams discussion-show host Phil Donahue has her in a segment on ""Women Who Lie to Their Parents.""
Blossom feels left out when Six befriends a chic new student; the kids keep Nick from seeing his divorce papers.
Prompted by old home movies Blossoms has transferred to video, the family retreats to the cabin by the lake where they'd shared happier times in the past.
Blossom blames herself for getting tricked into a date for the homecoming dance with a school "geek"; Joey wants to get his driver's license.
Nick gives Anthony an ultimatum: get a job or get out of the house.
Blossom leans on Six for support while calling a boy for a date; Anthony tries to help a friend stay sober; Nick gives Joey a hard lesson in mathematics.
Against her father's wishes, Blossom plans to drop out of her snooty private school and enroll in public school; Joey schemes to pass a history test.
Blossom and Six spy on a woman who claims a rattled Nick is the father of her child; Anthony preps for a blind date.