The fifth season of Criminal Minds premiered on CBS on September 23, 2009 and ended May 26, 2010. Episode 18 was a pilot episode for the spin-off series Criminal Minds: Suspect Behavior.
As Rossi, Morgan and JJ profile a killer who is targeting an emergency room doctor, Prentiss realizes that Hotch is missing.
The BAU must determine what caused a disturbed man to murder several people at a pharmacy before he harms anyone else.
The BAU investigates a case in Rossi's hometown that involves both his personal and professional life.
A group of suspects with a pack mentality who kill for the thrill of it are the subjects of a BAU manhunt.
The team hunts a suspect who impregnates young women and has them give birth before murdering them.
The BAU team tracks a serial killer who keeps the eyes of his victims as souvenirs.
The BAU team investigates the mystery behind a trail of murders that all seem to align with the tour schedule of a rock star.
The BAU team is tracking down a family annihilator, but needs to take a break from the case to get advice from "The Fox", who is an horrific killer from the team's past. "The Fox" surprises the team with a ominous message for Agent Hotchner.
The BAU team races to help Hotchner find The Reaper and save his family before it's too late.
The team needs to reunite in order to solve a home invasion case, while Agent Hotchner may have to leave the team.
The BAU is called upon to profile the past of an ex-convict and help stop him after he escapes from custody and embarks on a violent killing spree.
An unusual personal obsession is at the center of a BAU abduction case. Meanwhile, Hotch struggles with his return to work.
A rash of startling teen suicides in a small Wyoming town is the focus of a BAU investigation.
The BAU follows the mental decline of a con artist whose schemes have become so complicated that he begins to eliminate the people involved in them.
A serial killer who targets random victims in highly visible places to create a sense of public fear is the subject of a BAU investigation.
The BAU is called by local authorities in Ashburn, Virginia, to profile a predator who may have been abducting children for at least eight years.
A truck driver is kidnapping women and disposing of them in random locations and the BAU must find out his motive in order to catch him.
The BAU team travels to San Francisco to investigate the murders of several homeless men and teams up with a separate group of BAU operatives who are working another case they think is connected.
The BAU team heads to Texas to track a serial killer targeting illegal immigrants attempting to make safe passage into the U.S.
The BAU team must profile a serial killer covered in tattoos who commits suicide, but leaves clues to the whereabouts of his last victim.
Garcia plays a crucial role in a case when she travels to Alaska with the BAU team to investigate the murders of several members of a small town.
The BAU team profiles a serial killer who uses the Internet as his hunting ground, bringing a whole meaning to the term "social networking".
A series of rolling blackouts in the city of Los Angeles lures a serial killer out of hiding, giving him renewed opportunities to continue his killing spree.