Mayookham's story revolves around Unnithan (played by Saiju), the only son of Vasudevan Namboothiri and Devaki Andarjanam. Against the expectations of staid Namboothiri parents, Unnithan becomes the ring leader of the local band of hoodlums. All efforts turn him round are futile. In the course of their reckless lives, the gang members insult Indira (played by Mamta), who along with her friend Nalini had come to the local temple to worship. Indira, who has just returned from Australia, is the only daughter of Dr. Balakrishnan, a well respected person in the neighborhood. Indira however does not get provoked, because she recognizes Unni as her close childhood friend, even though he does not remember her. Her recollections of early childhood and her understanding of the present predicament of Unni's family, draws her to him, eventually changing him into a new persona.