No. 66 Madhura Bus is a 2012 Malayalam road movie. The film is directed by M. A. Nishad and stars Pasupathy, Padmapriya, Shwetha Menon, Mallika, Makarand Deshpande, Thilakan and Jagathy Sreekumar in pivotal roles. The screenplay is by noted author K. V. Anil. A journey of love and revenge, the film's story unfolds amidst the travel of an interstate bus.The film is directed by M A Nishad, who has earlier directed 'Pakal', 'Nagaram', 'Aayudham', 'Vairam' and quite recently 'Best of Luck'. 'No.66 Madhura Bus' is scripted by K V Anil, and has a stellar star cast that has such names as Pasupathy, Makarand Deshpande, Swetha Menon, Padmapriya Mallika and Rekha in it. And what's more; there is Thilakan, Jagathy, Jagadeesh, Ashokan, Kalpana, Seema G Nair Mahima and Kalinga Sasi, who would offer support to the leading cast. M Jayachandran would compose the musical score of the film and the lyrics will be penned by Vayalar Sharathchandra Verma & Rajiv Alunkal.