Claire (Maja Salvador) is a young interim doctor in a provincial hospital. Once, she encountered a female patient who is suspected of carrying a deadly flu virus. Afterward, she began to experience demonic visions, eventually, one demon entered her and began to take control on her. Claire's aunt (Gina Alajar) brings her to Father Ronnie (Mark Anthony Fernandez), who evidently was Claire's ex-boyfriend. Their relationship rekindles as they battle the demons out of Claire's body.