Set during the last days of the Tokugawa (Edo) Period, Moeyo-ken tells the story of Hijikata Toshizo and the Shinsengumi. Hijikata Toshizo is a samurai eager to test his skills and sword and make his first kill. The dojo he belongs to practices the Tennen Rishin style and teaches this to farmers. Not considered real samurai by other dojo's, they receive a request for a duel by a rival dojo practicing the Kogen Itto style. Sohaku Rokusha, a teacher there, challenges them and fights with Hijikata Toshizo. The outcome of the fight creates a deadly animosity between them that lasts through the ages.