Big Dog loses the can he's chewing on. After following the path it rolled down, they find it's now trapped behind an automatic door. After much thought, Little Dog concludes the door will not open for them because they're not wearing shoes. So they then go out hunting for shoes.
Little Dog is distraught. He's lost his favorite bone (which is actually just sitting on the back of his head). He asks Big Dog to help him find it and the two set out searching far and wide for the 'lost' bone.
The dogs wander onto a farm run by Hollywood. As Hollywood describes what the purpose of a farm is, the dogs get hungry and decide that they want breakfast: Cornflakes! Hollywood goes on to show them the whole agriculture process, while Big Dog simply plants a corn cob in the soil.
While walking along, Big Dog sticks his head in a hole in a fence. Little Dog panics and starts to devise a way to get Big Dog's head unstuck, but nothing seems to work. When all seems hopeless, Little Dog decides to adapt to life without Big Dog, but finds it impossible to do.
The dogs are headed to the Lucky Nugget to partake of the 'Super Cheap Economy Style One Pound Hot Dog Buffet'. But they're early, so they wait. The Big Dog finds a quarter and uses it in a slot machine. By stroke of luck, they win the jackpot, attracting the attention of casino owner Hollywood. Wanting to win his money back, Hollywood takes the dogs around to the other games. But the dogs just want the buffet, so they keep betting everything, only to win more.
While spending the day in the park, Little Dog happens upon a little toy dog that just barks twice, then does a flip. Little Dog interprets this as a sign of affection. Meanwhile, Big Dog is trying to return a frisbee to the girl who threw it to him.
It's show and tell at Kenny's school. He originally planned to bring his father's bowling trophy, but it breaks before he even gets on the bus. He then finds the two dogs and decides to bring them instead.
After seeing the intermission commercial for the concession stand on a drive-in theater screen(which has a hotdog, popcorn and soda- they all talk and dance!), the dogs conclude that the food must be just as big. So they go into the lot and get into all sorts of movie related hi-jinks.
The dogs investigate a truck full of what they think is ice cream. It's actually the food that's being stored in the next space shuttle. Once on board, the dogs accidentally launch the craft into space.
The dogs want to eat at the 'Pie in the Sky' restaurant. But they keep winding up at different stores in the mall that all employ Hollywood, who keeps selling the dogs products and telling them to just 'charge it'.
While passing a payphone with the phone off the hook, the dogs are told by the automatic teller to deposit 25�. Not wanting to disobey, the dogs then go in search for a quarter. This leads them to a cash machine, a trip to the psychiatrist, and a money making scheme.
The two dogs meet Red, who's off to her ill grandmother's house to give her some cheese cake. But the dogs lead her to the Three Bears house where they eat their porridge, sit in their chairs, and sleep in their beds.
Kenny's regular school teacher is on sick leave (nervous breakdown), so Mr. Hollywood (or Mr. H.) is substituting. But he's in for a challenge when he meets Kenny and his class.
The dogs are sold as seeing eye dogs to Hollywood, who's blind after an eye exam, but Big Dog is more concerned with finding a fire hydrant, while Little Dog keeps claiming he knows a shortcut, which involves going through a construction yard.
The Little Dog wants to recover some bones he's buried in the 'Paws and Reflect' pet cemetery. But his head becomes stuck inside a skull, the Big Dog becomes afraid of him and hides.
The dogs are mistaken as farm hands on Farmer Hollywood's farm. Wanting breakfast, the dogs must first learn how to 'round up the doggies' to earn their meal.
It's garbage day, and the two dogs scrounge through a trash can for things. but a heated debate ensues when they find a used toilet seat that both of them want.
Hollywood is Noah, building his Ark and gathering two of every animal. When it comes time to get two dogs, he finds Big Dog and Little Dog. But the two prove to be very taxing on Hollywood and the rest of the animals.
The dogs happen upon a little home that's having a cook-out. Upon investigating, they find a family that's very Brady Bunch-esque. The family is getting into situations that they're 'learning from'.
The dogs are once again tempted to follow Red (this time with the promise of BBQ-flavored canned cheese). They wind up at the witch's house from Hansel and Gretel. There, they are forced to feed Red until she is ready to be eaten.
The dogs try to get into a dog food commercial for the free food, but they accidentally wander into the wrong studio where they're filming a jungle picture. It stars Hollywood, and he mistakes the dogs for the stunt doubles for jungle king's faithful sidekicks: Bo-Bo and Boo-Boo.
The two dogs are hungry and want Happy Granny dog food. But it belongs to Red who's once again off to Grandma's house. Upon arrival, Red gives the wolf the classic interigation, while the wolf fights with granny in his stomache.
For no apparent reason, the two dogs switch bodies. Noticing no effect, the two set out in search for food only to find their new bodies are non-compliant with their stupid personalities.
The two dogs are in search of some doggie biscuits, and they wind up being contestants on the show "Let's Make a Right Price", with Billy Baker. The losers get doggie treats, so the dogs try to avoid winning the real prizes. The dogs bet one dollar each round, but manage to win every time. Will that strategy work?
Big Dog is sleeping and Little Dog is in trouble. A cat has wandered into the alley and has placed itself between the two dogs. With Little Dog's dependence on Big Dog's ability to scare cats, he must find a way to wake Big Dog from the other side of the cat.
The dogs are hanging out with Kenny, who's in love with Buffy. But Kenny is too nervous to talk to her, so the dogs talk to her for him. But Little Dog misinterprets everything Buffy's says, leading Kenny on. Soon, Buffy is playing with Kenny and the dogs, but only because she thinks the dogs belong to him.