Based on Neil Gaiman's 2001 novel of the same name, ex-convict Shadow Moon becomes the traveling partner of a mysterious conman named Mr. Wednesday after his release from prison. He soon discovers Mr. Wednesday is more than he seems and becomes embroiled in an epic conflict between Old Gods and New.
When Shadow Moon is released from prison early after the death of his wife, he meets Mr. Wednesday and is recruited as his bodyguard. Shadow discovers that this may be more than he bargained for.
As Mr. Wednesday begins recruitment for the coming battle, Shadow Moon travels with him to Chicago and agrees to a very high stakes game of checkers with the old Slavic god, Czernobog.
Shadow questions his decision to work for Mr. Wednesday after learning of his plan to rob a bank. Shadow makes a surprising discovery when he returns to his motel room.
The story of Laura's life and death is explored, including her first encounter with Shadow and how exactly she came to be sitting on the edge of his motel room bed.
Shadow's emotional reunion with his dead and unfaithful wife is interrupted when he and Mr. Wednesday are kidnapped by the New Gods.
On the run after the New Gods' show of force, Shadow and Mr. Wednesday seek safe haven with one of Mr. Wednesday's oldest friends, Vulcan, God of the Fire and the Forge.
Following her brief reunion with Shadow, Laura turns to an unlikely travel companion to find her way back to life; Mad Sweeney's long, winding, and often tragic past is explored.