A new teen comedy for Nickelodeon starring Drake Bell and Josh Peck. This is a spin off of The Amanda Show, a cancelled Nickelodeon variety show starring comedy actress Amanda Bynes. Drake and Josh were actors on the show.
15-year-old Drake and Josh are schoolmates, but not close friends. Drake views Josh as weird and a bit of a goof. So, imagine Drake's shock when he finds out that this "goof" is about to become his new step-brother and roommate when his mother marries Josh's father.
Drake and Josh both find out that Drake's Mom, and Josh's Dad, get married to each other unexpectedly. Drake finds it completely wrong. And Josh on the other hand is really excited. Right as Drake things his life is miserable, things get better. He discovers that Josh is actually Miss Nancy, a person who gives advice in the school newspaper.
After reading one of Josh's Miss Nancy letters, Drake discovers that Tiffany (the girl he likes) is having trouble with her boyfriend. Drake uses this advantage to go on a date with her. But Tiffany's real boyfriend gets things confused, and thinks Josh is dating Tiffany! Now Josh must study to be excellent at karate before Tiffany's boyfriend scars him for life.
Josh gets grounded because of something Drake did. The boys later receive a broken dune buggy from Trevor, a friend of Drake's. In Josh's free time, he fixes the dune buggy. One day, Drake drives the dune buggy (against his parent's wishes, and without their knowledge), but he runs into a tree, getting several injuries. He hides his injuries from his family using makeup, but Josh soon finds out what had happened and blackmails him until he tells the truth.
Susan, Drake's girlfriend flirts with Josh, constantly kissing him, but Susan is such a good liar that when Drake is around she makes Drake think Josh is hitting on her.
Drake and Josh have to babysit their Dad's boss's son. The baby disappears and Josh panics while Drake leaves to play in a concert. Drake comes back to help Josh, and finds out that Megan has had the baby the whole time.
Josh tries to impress his first crush Kathy, but gets so nervous he accidentally says he can play the guitar. Drake, meanwhile, gets kicked out of the restaurant his band played in (due to Megan's new snake.) Kathy asks Josh to play the guitar for her at her birthday party (which, coincidentally, happens to be at the same restaurant Drake got kicked out of), Drake and Josh work out a plan so that Josh can impress Kathy and Drake can get back into the restaurant, called the Brew Note. The guy who taught Josh karate owns the restaurant.
Drake and Josh's parents are going away for the weekend and Drake and Josh are excited because they think they can do what they want. But when Josh's Grammy comes to babysit Josh is enjoying it, but not so much Drake. Grammy won't let Drake out of the house to see a concert, so he sneaks out.