Benton Fraser comes to Chicago in an attempt to find out who killed his father. After solving the murder, he decides to stick around and work for the local Canadian consulate. He has made friends with a local detective, Ray Vecchio, whose sister, Francesca, has a major crush on him. Although Vecchio is often confused by Benton's strange way of doing things and Benton is often confused by how things are done south of the border, the two get along famously.
A plane crash blinds Fraser and strands the pair in the wilderness. Fraser and Ray's vacation to Canada to rebuild his father's cabin doesn't go as planned when it turns out the pilot of their airplane is actually an escaped felon. The felon jumps out of the plane, causing it to crash. Fraser is blinded in the crash, and eventually loses the use of his legs. Ray tries to carry Fraser out of the woods, and the two cops still have to catch the felon, while dealing with the ghosts of their two fathers.
During a bank robbery, Fraser and Ray are trapped in a time-locked, water-filled vault. After Ray is declared dead due to a mix-up with the insurance company, Fraser and Ray go to Ray's bank, where the end up in the middle of a robbery, running into someone they've met before...Morgan. Fraser and Ray lock themselves in the vault and Fraser sets off the sprinkler system, hoping to hit the criminals with a tidal wave of water. Meanwhile, Frannie is waiting in Ray's car outside, and enters the building, thereby becoming a hostage.
Ray is jailed for contempt of court; Fraser gets arrested to protect him.
Fraser must see that a federal witness comes safely to trial.
A teenage thief's life is put in danger when she steal an appointment book which could destroy a powerful senator's career, and Fraser and Ray have to save her.
When valuable aboriginal masks are stolen from a museum, Fraser and Ray have to find the culprits.
Ray is convinced that he's found Guardino's killer in mafia boss Frank Zuko, but is torn when he realises he's the brother of his childhood sweetheart, Irene Zuko.
Fraser rallies the tenants to do something about the current situation, but when they get the landlord's attention, he evicts them all. In order to fix what he did, Fraser then goes in front of city council.
Ray and Fraser team up with Anita Cortez to protect their countries diplomats at a NAFTA convention, and a series of mishaps land Fraser with envelope duty, until he and Cortez can put aside their mutual enmity to work together.
Ian MacDonald claims aliens kidnapped his girlfriend Audrey as he was about to propose. Ray and Fraser reluctantly investigate, and learn that Audrey is involved in a shady government organization.
Ray and Francesca fight over a winning lottery ticket...she wants half the winnings because she put in half the money, and he says it's all his money because he purchased the winning ticket solely with his own money. After accidentally creating an accident with a local farmer, Fraser is sued by him, and later learns he's created a special brand of egg that everyone wants.
Fraser goes undercover as a woman at a girls' school after Ray's ex-girlfriend comes to him for help. Ray, meanwhile, worries that he turned his ex into a nun.
A teen takes the rap for a drug dealer but Fraser and Ray are determined to prove his innocence.
Terrorists take a train carrying a group of singing mounties.
An exotic dancer tells about mobsters taking over strip joints.
A paroled killer leaves clues about his next victims for Ray.
Terrorists strap Fraser and Ray to a bomb.
Fraser has amnesia after being thrown from a speeding van driven by diamond thieves and forgets everything -- his name, his identity, and the license plate of the speeding van. Ray tries to prod Fraser's memory by recounting some of their times together.