Edgar and Ellen live in a 13-story mansion on the edge of Nod's Limbs. Ellen is older by 2 minutes and 13 seconds. They live with a hairy creature who they refer to as Pet — a hairball with an eyeball. Their groundskeeper and caretaker, Heimertz, lives in a small shack just outside the house. Their mansion is located near a now disassembled junkyard, which the twins had lovingly dubbed their "Gadget Graveyard". They take parts from it and create marvelous contraptions for trouble.
Both of the twins wear striped footie pajamas and prank each other all day long—when they're not pranking the goody-goody townspeople of Nod's Limbs. They are clever, fearless, mischievous and creative. So creative, in fact, that their pranks often backfire hilariously.