Angolan Queen Nzinga's rise, rule, and campaign against Portuguese colonization.
Nzinga didn't start out as a queen--but when she saw how incompetently her brother was running affairs in Ndongo (what would become Angola), she took advantage of his decision to send her to negotiate with the Portuguese--much to his grief later. Nzinga established herself against colonial forces and did not budge.
Nzinga was briefly, temporarily supplanted by Ngola Hari who had been installed by the Portuguese, but she was determined to let nothing get in the way of keeping West Africa safe from colonial powers. To achieve this end, she would go on to form--and break, as she pleased--alliances with the Dutch, the Imbangala, and even the Catholic Church!