Sick, twisted, politically incorrect and Freakin' Sweet animated series featuring the adventures of the dysfunctional Griffin family. Bumbling Peter and long-suffering Lois have three kids. Stewie (a brilliant but sadistic baby bent on killing his mother and taking over the world), Meg (the oldest, and is the most unpopular girl in town) and Chris (the middle kid, he's not very bright but has a passion for movies). The final member of the family is Brian - a talking dog and much more than a pet, he keeps Stewie in check whilst sipping Martinis and sorting through his own life issues.
In order to compete with ambitious friends, the Griffins decide to climb Mount Everest.
When the Griffins are selected to have their TV-watching habits monitored, Peter hatches a scheme to control the airwaves.
Brian learns that Carter Pewterschmidt's company is keeping the cure for cancer from the public in order to drive up profits; Quagmire reveals a secret.
When Brian accidentally causes Stewie's time machine to make reality run in reverse, the two must fix the problem before Stewie is unborn.
When the criminal who put Joe in the wheelchair becomes a fugitive, Quagmire, Joe and Peter try to hunt him down.
Peter tries to keep up with Lois as she goes through a midlife crisis; Stewie brings home a turtle from the park.
When Meg learns her crush is gay and interested in Chris, she uses her brother to get closer to him.
As the Griffin family is preparing for Christmas, Peter tells his own version of the Nativity story.
When the Griffins try to pick Chris up from space camp, they find themselves accidentally launched into space and reliant on Chris to get them home.
Brian writes a play that becomes a hit in Quahog, but loses his confidence when he finds that the play Stewie wrote is better than his.
During a visit to Harvard, Quagmire accidentally marries a prostitute; in an attempt to get out of his marriage, Quagmire pretends that Peter is his lover.
On Valentine's Day, Meg goes on a date with a guy she met online, and Lois and Peter stay in bed all day; Brian is visited by his ex-girlfriends.
When Meg catches Chris stealing money from Lois' purse, she makes him do her chores; Chris, tired of the pact with Meg, runs away to live with Herbert; Stewie and Brian become obsessed with singer Anne Murray.
When Lois gets a job at an adults-only phone line to earn extra money, she takes a call from Peter.
An unfortunate sky-diving accident sends Peter to the hospital, where he makes friends with a man named Mahmoud; Quagmire and Joe become suspicious of Mahmoud.
Mayor West becomes the prime suspect when a murder occurs at his mansion.
When Peter resurfaces after being in a plane crash and lost in the wilderness for two months, his family must find a way to bring him back from his animal-like state.
When teddy bear Rupert is recalled, Stewie is determined to get his best friend back; when Peter is sick and can't compete in a bowling tournament, Lois fills in for him.
Peter and the guys try to save The Drunken Clam from being closed after the bar's owner dies; Meg gets a job at a funeral home.
The Griffins move to a farm, where Peter starts a drug business.
Stewie's teleportation machine malfunctions when he and Brian use it to travel to Las Vegas for a Celine Dion concert.
When Chris make the acquaintance of the daughter of the owner of the Barrington Country Club, the Griffins are introduced to the new club lifestyle much to the chagrin of Carter.
Carter eventually gets kicked out of Barrington and Peter agrees to help him get back in.