The tenth season of Frasier originally aired from September 9, 2002 and May 20, 2003 on NBC. A disclaimer appears on the backside of the Season 10 DVD box which states "Some episodes may be edited from their original network versions". However, it is unclear as to which episodes were edited, whether these are the syndicated versions, or whether music was replaced for certain episodes due to licensing issues.
After Daphne and Niles elope in Reno, they are forced to go through several fake ceremonies in not to upset friends and family who wanted to be at the wedding.
Frasier drives Niles back from shopping, realising he is going to be late for his show Frasier drives in and out of the garage. Forced to pay for this drive through, Frasier stages a parked protest.
Frasier is desperate to finally win the presidency of the condo board after several unsuccessful attempts. However, he admits that he has no chance because he has rubbed all of the board members the wrong way at one time or another. He decides to get Martin run with the proviso of following his agenda.
Frasier is surprised to learn that Kenny has never unpacked the boxes in his office because he views all of his jobs as temporary. Roz's younger cousin Jen comes to stay with her for the week.
Frasier is infuriated when Bulldog successfully pulls several practical jokes on him. He vows to get revenge, and plots an elaborate prank that he takes way too seriously. Martin and Roz predict that he will fail because he is terrible at carrying out pranks. Frasier seeks the help of an unlikely ally to prove them wrong. Meanwhile, Mrs. Moon wages a prank war of her own against a trick or treater who eggs Niles' door after he forgets to buy Halloween candy.
As Frasier prepares for Frederick's bar mitzvah, Noel offers to translate Frasier's speech into Hebrew in exchange for an autograph from a science fiction convention. However, when Frasier doesn't keep his end of the bargain, Noel uses his wealth of Star Trek knowledge to take revenge.
Niles becomes concerned about a lingering toothache after his dentist assures him that there is nothing wrong with the tooth. He tells Roz that there is a chance that he may be suffering from referred pain; and that the pain could actually be a sign of a heart condition. Roz mocks him upon learning that there is only a one in 10,000 chance of this. However, Niles worries even more after experiencing a series of astonishingly improbable events--such as having his car struck by lightning, and twice winning a contest from a bottled water company for which there is only one winner in 10,000. He goes to see a doctor, who confirms his worst fears by telling him that he must be hospitalized immediately due to an irregularity in his EKG. Meanwhile, Frasier has difficulty finding a suitable housekeeper to replace Daphne. Martin is impressed by a young woman who is a sports fan; and insists on hiring her, in spite of Frasier's objections. However, she proves to be totally irresponsible, and rarely even shows up for work. Martin tries to handle all of her duties himself so that he won't have to admit that Frasier was right about her.
Niles prepares to undergo heart bypass surgery. He is surprised to receive a call wishing him well from Maris, who had learned of his plight from a gossipy acquaintance. Frasier tries to keep Roz and the family at ease by researching the procedure (as well as the doctors' backgrounds) and printing out detailed descriptions for everyone. However, he winds up getting on the surgeon's nerves by questioning his approach to the operation. Martin tries to act as though everything is fine so that he doesn't have to deal with the fear and uncertainty of the situation. Roz tries to help the terrified Daphne stay calm. She refuses to think of other things, stating that she has no future until she knows that Niles is all right. Niles' drug-induced comment about the possibility of hospitals having "memories" about their patients prompts everyone to think back on past experiences in that hospital, from Niles' birth to a time that Roz mistook lipstick on Alice's cheek for a rash. Daphne grows more and more tense as they await word on the surgery. When Martin and Frasier repeatedly bicker about a candy bar stuck in the vending machine, Daphne smashes the machine with a fire extinguisher. She breaks down crying, and everyone does their best to console her. Niles' surgery goes even better than expected, and he begins his recovery. A relieved Daphne is finally able to bring herself to think about their future.
Niles recovers rapidly from his heart surgery and receives the go-ahead from doctors to resume normal activities, but seems reluctant to do this. He maintains his strict post-operative diet, and refuses to exercise or share a bed with Daphne. He annoys everyone by constantly going around making speeches about his near-death experience and how much he appreciates life. Frasier refuses to argue with Niles because he promised God that he would never quarrel with his brother again if he recovered from his sickness. The frustration of having to agree with everything Niles says begins to drive Frasier crazy, especially when Niles starts monopolizing his radio show to give his own advice to callers. Frasier believes he has found a way to back out of his promise after he learns that Daphne had already made her own deal with God. In the meantime, Martin talks with Niles about the feelings he experienced after his shooting, and forces his son to overcome his fears and go on with his life.
Frasier and Niles bicker over who gets to host the family Christmas celebration. When it seems that Martin will have to work, they decide to bring Christmas to him, with disastrous results. Meanwhile, Roz finds herself attracted to a hunky shopping mall Santa.
Frasier mistakenly receives some of Cam Winston's mail, including a mysterious invitation to an exclusive locale. Frasier and Niles are surprised to have been left out of the loop about this new hot spot, and become obsessed with finding out more information. Frasier heads to the address on the invitation, but cannot get the receptionist to tell him anything. Niles finally shows up and poses as Cam, and is told that the business is a spa. He and Frasier enjoy all of the amenities, but are disturbed to learn that the spa has a "gold level" area to which they are denied access. They constantly complain about being left out. Roz believes that they only care about the gold level because they are not allowed there, but uses her connections to a senator who has a membership to get them inside. The brothers are appeased, until they spot a platinum door. They ignore an attendant's warning and barge through the door, but aren't too happy with the result. Meanwhile, Daphne ruins Martin's enjoyment of The Rockford Files when she says that he reminds her of Rockford's father, rather than the title character.
Frasier is forced to give up ten minutes of his show for a new financial analysis segment. When the beautiful new stock market reporter's attitude rubs everyone the wrong way, Frasier misreads her signals, which lands everyone in a sexual harassment seminar.
Lilith comes to Seattle, and tells Frasier that she would like to have another child. She wants him to father the child through artificial insemination so that Frederick could have a full-sibling. Frasier is hesitant to go along with this, so Lilith tries to manipulate him by bringing up touching stories from Frederick's childhood. She says that creating another person as wonderful as Frederick would be the best possible legacy they could leave. Frasier agrees to do it, much to the surprise of his family. When Frasier and Lilith argue at the clinic, he begins to fear that their second-born could inherit all of their worst qualities. He believes that they are trying too hard to re-create the past. He doesn't feel this would be a good reason to bring a child into the world. Frasier worries that Lilith is missing something from her life. However, she seems to make a connection with a fellow passenger, whom she had first met on the trip to Seattle, during her flight home. Meanwhile, Daphne, Roz, Mrs. Moon and Alice embark on a road trip to a Canadian amusement park, with disastrous results. Niles obsesses over a blurry photograph at the end of a roll, which he believes to be an illicit photo of Daphne. He is more than a little disturbed when he discovers the truth.
Niles and Frasier plan a party to celebrate the unveiling of a painting that Niles has just purchased. However, Daphne notes that every event the brothers host inevitably ends in disaster. She suggests that Niles instead host the party with her. Frasier is hurt to learn that he will be excluded, and says that he will not even attend the party. Daphne believes that she has everything under control, but things quickly begin to unravel. Alice writes her name in crayon on the painting. Daphne remains calm, and gives Roz the name of a man whom Niles uses to restore artwork. However, the game hens catch fire in the meantime. The caterers are too busy to replace them, so Daphne must turn to Frasier for help. He comes over to assist with the food preparation, but must hide in the pantry whenever Niles comes in the kitchen so that his role will remain a secret. Frasier becomes angry when he overhears Niles and others complimenting the food and saying how much better off they are without Frasier's involvement. Mike Shaw, the artist responsible for the painting, shows for the party after earlier declining his invitation. He doesn't care for the stuffy guests, and decides to go upstairs and watch pay-per-view boxing with Mrs. Moon. Niles hears a couple's description of Shaw (white-haired man in a flannel shirt using a cane) and assumes they have him confused with Martin. The couple who met Shaw has to leave. Martin arrives to bring Frasier some dishes, and winds up having to pose as Shaw for the other guests. Roz asks Daphne to stall the unveiling because the art restorer is painfully slow. Niles insists that dinner must be served immediately. He discovers Frasier, and they begin to argue, leading to more chaos. Daphne tries her best to salvage the evening, but an unexpected event prompts her to give up. Frasier consoles her by telling her that the disastrous party means she is officially part of the family.
Tired of being humiliated in his club's annual squash tournament, Niles ditches Frasier and pairs with a younger partner. A P.E. teacher named Chelsea asks Frasier to team with her in the mixed doubles competition. They win the championship. Martin is overjoyed that one of his sons has finally earned a trophy for athletics. Niles winds up begging for Frasier to take him back after his new partner yells at him on the court. Frasier assumes that the tournament's conclusion means the end of his relationship with Chelsea, but they soon begin dating. Niles is surprised that Frasier would date a P.E. teacher after all of the abuse the brothers endured in gym class as children. When Frasier goes to Chelsea's school to pick her up, he sees her berating one of the students. This causes him to have flashbacks, and he can no longer look at Chelsea without seeing his old gym teacher, Coach Fuller. Frasier tries to convince Chelsea to be more sensitive to the children. Meanwhile, Frasier tries to persuade Roz and Julia to be more civil to one another. They cannot find any common ground, until they realize how much they enjoy insulting each other.
KACL organizes a bike-a-thon to raise money for AIDS research. Frasier plans to just make a financial donation, but is goaded into participating after Julia announces her intention to take part. Daphne suggests that she and Niles also enter the event. Frasier and Niles try to hide the fact that neither of them knows how to ride a bike, and hope that they can figure it out before the bike-a-thon. After the truth comes out, Daphne tries to help them, but finds that it isn't easy. Meanwhile, Martin receives a frosty response from Cam Winston's mother, Cora, when she comes to the building to visit her son. When he asks why she never called, he learns that Mrs. Moon posed as his girlfriend and scared her away. Martin explains the situation, but Cora already has a boyfriend. A furious Martin gives Mrs. Moon the silent treatment, but she eventually goes to Cora to make amends.
Kenny becomes extremely depressed after his divorce is finalized. Frasier offers to refer him to another psychiatrist, but Kenny says that he would prefer to discuss his problems with Frasier. Frasier reluctantly agrees, but doesn't take any money. Frasier is thrilled about getting to work with a patient again, and quickly delves into Kenny's childhood issues and cites them as the source of his relationship problems. Kenny remains depressed, so Martin lets him tag along to McGinty's. They have a good time drinking and hanging out. Kenny decides to follow Martin's advice and start getting out of the house so that he can take his mind off his problems. He tells Frasier that he doesn't want to come in to see him anymore. Frasier is furious with Martin, and takes issue with his father's comments about psychiatry. However, Martin finally reminds him that Kenny is far from the only person with problems, and suggests that Frasier start treating patients again. Meanwhile, Niles and Daphne begin practicing yoga with an instructor who caters to Seattle's elite. Although he won't admit it, Niles grows jealous when Daphne proves to be much more flexible than he is.
Frasier and Niles become a big hit when, at a party, they serve beluga caviar they purchased on the black market. Meanwhile, Martin has a tough time returning $40 an ATM gave him in error.
Frasier's co-workers cajole him into helping them build a house for Habitat for Humanity. Frasier mostly seems to get in the way, and his participation is limited to stirring paint and a little bit of sanding. However, he somehow views himself as having played some huge role in the process. He becomes very attached to the house, and keeps showing up to offer the inhabitants unwanted decorating advice. Roz tries to convince him that they should be allowed to furnish and decorate the house in whatever way they see fit. Martin and Eddie give a presentation about safety to an elementary school class. They are a big hit, and the school asks them to return for an assembly. However, Martin comes down with a fever and is unable to go through with the speech. A reluctant Niles is forced to take his place. He blames the children for making Martin ill, and winds up impressing the kids with a lecture about germs. Daphne and Mrs. Moon get into a huge argument about her mother's increasingly difficult behavior. After Daphne suggests that she help around the house, Mrs. Moon responds by getting a job at Cafe Nervosa. She hopes to publicly embarrass Daphne and shame her into apologizing. Daphne, however, is nonplussed by her mother's behavior and gladly accepts her paycheck.
Frasier consults his old friend Avery for advice on his finances. Avery says that Frasier's spending habits are out of control. Frasier becomes depressed and heads out to Cafe Nervosa to think about a solution. He is disgusted to discover that the owner has hired an eccentric folk singer to perform every afternoon.
Frasier learns that Dr. Phil McGraw is in town for a special. The two are old friends, but Frasier is angry at Phil for supposedly swindling him out of $200 in a poker game.
Leland Barton, Hester's former research assistant, comes for a visit after a long absence from Seattle. Roz becomes alarmed when Leland confesses his deep affection for Hester.
Julia becomes extremely depressed after breaking up with Avery, who had never followed through on his promise to leave his wife for her.
Roz tries to train the woefully incompetent Noel as Frasier's new producer as she prepares to leave KACL.