After a quarter-century of political denial and social stigma, of stunning scientific breakthroughs, bitter policy battles and inadequate prevention campaigns, HIV/AIDS continues to spread rapidly throughout much of the world. Through interviews with AIDS researchers, world leaders, activists, and patients, FRONTLINE investigates the science, politics, and human cost of this fateful disease and asks: What are the lessons of the past, and what can be done to stop AIDS? In the conclusion, of ?The Age of AIDS? Dr. David Ho's development of an AIDS drug ?cocktail,? and his belief (with five million new cases each year) that neither he nor his children will live to see the end of AIDS. Also: the efforts of Rev. Franklin Graham; Bono's activism and how the rock star got Sen. Jesse Helms to change his views on AIDS; the disease's impact in South Africa, Uganda, Brazil, China and Russia.