Hamilton's Pharmacopeia

All Episodes 2012 - 2021
TV-MA

  • Ended
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  • 2016-10-27T02:00:00Z
  • 44m
  • 14h 40m (20 episodes)
  • Hamilton Morris
  • United States
  • English
  • Documentary
Join an incredible journey through the history, chemistry and societal impacts of the world’s most extraordinary drugs.

39 episodes

There is an Amazonian frog called Phyllomedusa Bicolor or the Sapo which I have been reading about for years. It is totally different from the psychedelic toads found in North America. The Sapo's venom produces an effect much closer to morphine than LSD, but really it's not like either of those things. It's a distinctly vomitous dissociative experience unlike anything else I've ever encountered.

There is an Amazonian frog called Phyllomedusa Bicolor or the Sapo which I have been reading about for years. It is totally different from the psychedelic toads found in North America. The Sapo's venom produces an effect much closer to morphine than LSD, but really it's not like either of those things. It's a distinctly vomitous dissociative experience unlike anything else I've ever encountered.

There is an Amazonian frog called Phyllomedusa Bicolor or the Sapo which I have been reading about for years. It is totally different from the psychedelic toads found in North America. The Sapo's venom produces an effect much closer to morphine than LSD, but really it's not like either of those things. It's a distinctly vomitous dissociative experience unlike anything else I've ever encountered.

Special 4 Underground LSD Palace

  • 2012-05-25T02:00:00Z44m

Former goth stripper Krystle Cole talks about her time spent living in a subterranean missile silo converted into a luxurious LSD manufacturing facility. She spent three years of her life running from the DEA, being held partially against her will and used as a guinea pig for strange new psychedelic chemicals. Eventually her friends-turned-captors were arrested and Krystle herself barely escaped incarceration. She now makes her living as a writer, sharing her experiences in books and on the web.

Rumor has it that there is a secret drug in Haiti that can turn the living into Zombies. In part 1, Hamilton takes off for Port-Au-Prince on a quest for the secret poison.

Rumor has it that there is a secret drug in Haiti that can turn the living into Zombies. In part 2, we attended a Voodoo ceremony and watched as a pig was sacrificed in order to become an ambassador to the gods.

Rumor has it that there is a secret drug in Haiti that can turn the living into Zombies. In part 3, we were granted a meeting with the leader of the Bizangos, a Haitian secret society and beholder of the formula for zombification. Negotiations are made and a local Bokor agrees to create a nzambi—for a price.

Rumor has it that there is a secret drug in Haiti that can turn the living into Zombies. In part 4, we went searching for the secret ingredient in the zombification powder, a poison extract from the Tetraodontidae, also knows as the Pufferfish.

Rumor has it that there is a secret drug in Haiti that can turn the living into Zombies. In part 5, Hamilton takes a large dose of the zombie powder to prove his strength. He is rewarded with a peak inside a zombie's shed.

Rumor has it that there is a secret drug in Haiti that can turn the living into Zombies. In part 6, Hamilton procures a sample of the zombie powder and its mysterious antidote. He returns home to subject both to extensive chemical analysis.

We took a trip to Amsterdam to learn about the ban of psychedelic mushrooms and the rise of truffles that contain psilocybin (the stuff that makes you trip balls).

The best way to eliminate all sensory input is to step inside a sensory deprivation tank. In part 1, we talk to Joe Rogan about what happens to the mind, body, and spirit while inside the tank.

The best way to eliminate all sensory input is to step inside a sensory deprivation tank. In part 2, VICE Correspondent Hamilton Morris spends five hours inside a tank only to come out with more questions than answers. We head to Isolation Floatation in Colorado to learn more.

The best way to eliminate all sensory input is to step inside a sensory deprivation tank. In part 3, VICE correspondant Hamilton Morris tests the Rolls Royce of sensory deprivation tanks at Cloud nine Float Center in Boulder, Colorado.

Zolpidem tartrate, or Ambien, has been prescribed to millions of insomniacs internationally, yet those who use the drug to ensure a good night's sleep are seldom aware it also possesses the ability to normalize functioning in certain types of damaged neurons, a phenomenon called "the Ambien effect." The first awakening occurred in 1999 when a man who had spent three years in a persistent vegetative state spontaneously regained consciousness after ingesting a 10mg tablet. Since then, hundreds of patients have experienced miraculous recoveries from traumatic brain injury using Ambien. Hamilton Morris travels from South Africa, where the Ambien effect was first discovered, to England to interview a physician on the cutting edge of Ambien research, and then to Florida to meet a voice-over artist who depends on Ambien to speak.

Swaziland is a landlocked country sandwiched between South Africa and Mozambique. Despite Swaziland's small size, it boasts more hectares of land dedicated to growing Cannabis than all of India. It is also home to Swazi Gold, the legendary sativa strain. Hamilton Morris travels to Swaziland hoping to chemically analyze the cannabinoids present in some of the local strains. Instead, he finds a country steeped in political corruption and economic turmoil. Cannabis is viewed by many growers, users, and politicians as a drug that will cause insanity, but it may be Swaziland's only hope for economic stability.

Swaziland is a landlocked country sandwiched between South Africa and Mozambique. Despite Swaziland's small size, it boasts more hectares of land dedicated to growing Cannabis than all of India. It is also home to Swazi Gold, the legendary sativa strain. Hamilton Morris travels to Swaziland hoping to chemically analyze the cannabinoids present in some of the local strains. Instead, he finds a country steeped in political corruption and economic turmoil. Cannabis is viewed by many growers, users, and politicians as a drug that will cause insanity, but it may be Swaziland's only hope for economic stability.

In 1998, the antiretroviral drug efavirenz was approved for treatment of HIV infection. Though the drug was highly effective, patients soon began to report bizarre dreams, hallucinations, and feelings of unreality. When South African tabloids started to run stories of efavirenz-motivated rapes and robberies, scientists began to seriously study how efavirenz might produce these unexpected hallucinogenic effects. Hamilton Morris travels to South Africa to interview efavirenz users and dealers and study how the life-saving medicine became part of a dangerous cocktail called "nyaope."

Hamilton Morris travels to New Zealand to meet the king pin of New Zealand’s legal highs crusading for his fading dream for future of drug control.

Series Premiere

2016-10-27T02:00:00Z

1x01 The Story of the South African Quaalude

Series Premiere

1x01 The Story of the South African Quaalude

  • 2016-10-27T02:00:00Z44m

South Africa is the last place on earth Quaaludes can still be found; Hamilton travels there to study the drug and learns of a dark history of medical experimentation.

2016-11-03T02:00:00Z

1x02 A Positive PCP Story

1x02 A Positive PCP Story

  • 2016-11-03T02:00:00Z44m

Hamilton investigates the history of PCP in the U.S., seeking input from addicts, dealers and chemists.

From the heavenly cloud forests of Oaxaca to a viral video of Miley Cyrus, Hamilton investigates the inconspicuous yet extraordinary psychedelic plant Salvia divinorum.

2016-11-17T03:00:00Z

1x04 Magic Mushrooms in Mexico

1x04 Magic Mushrooms in Mexico

  • 2016-11-17T03:00:00Z44m

Hamilton explores magic mushrooms with the help of shamans, clandestine growers, and ethnomycologists.

2016-12-01T03:00:00Z

1x05 Fish N' Trips

1x05 Fish N' Trips

  • 2016-12-01T03:00:00Z44m

Hamilton embarks on an aquatic adventure to Reunion Island and Madagascar to investigate ichthyoallyeinotoxism and a twisted history of hallucinogenic fish.

Season Finale

2016-12-08T03:00:00Z

1x06 The Lazy Lizard School of Hedonism

Season Finale

1x06 The Lazy Lizard School of Hedonism

  • 2016-12-08T03:00:00Z44m

We meet with famed LSD chemist Casey Hardison in the Nevada desert and embark on a roadtrip to visit the unsung hero of psychedelic history.

Season Premiere

2017-11-29T03:00:00Z

2x01 The Psychedelic Toad

Season Premiere

2x01 The Psychedelic Toad

  • 2017-11-29T03:00:00Z44m

Hamilton embarks on a quest to answer the most important question in ethnoherpetological history and along the way, he finds the power of love.

From the greenhouses of Thai cactophiles to the Tamaulipan thornscrub, Hamilton traces the history of peyote with the help of a Native American peyotist.

2x03 Kratom: The Forbidden Leaf

  • 2017-12-13T03:00:00Z44m

Hamilton investigates the pharmacology and traditional uses of Kratom, a Thai tree with opioid-containing leaves.

2017-12-20T03:00:00Z

2x04 Wizards of DMT

2x04 Wizards of DMT

  • 2017-12-20T03:00:00Z44m

Hamilton travels across North America to study how and why DMT exists in the environment and the laboratory.

Hamilton heads to India to see industrial Ketamine synthesis, and speak with therapists and luminaries in an attempt to understand the role of dissociative anesthetics in society.

Hamilton meets an unsung hero of the psychedelic underground and hears a tragic tale of MDMA synthesis and chemiluminescence.

2018-01-10T03:00:00Z

2x07 A Fungal Fairy Tale

2x07 A Fungal Fairy Tale

  • 2018-01-10T03:00:00Z44m

Hamilton ascends the Carpathian Mountains, microscope in hand, to learn how Europeans use Amanita muscaria, and uncovers the chemistry behind a mushroom-inspired pharmaceutical.

Season Finale

2018-01-17T03:00:00Z

2x08 The Cactus Apprentice

Season Finale

2x08 The Cactus Apprentice

  • 2018-01-17T03:00:00Z44m

Deep in the Andean highlands of Peru, Hamilton becomes the apprentice of a local shaman, learning how to use the night-blooming San Pedro cactus as a medicine.

Season Premiere

2021-01-05T03:00:00Z

3x01 Synthetic Toad Venom Machine

Season Premiere

3x01 Synthetic Toad Venom Machine

  • 2021-01-05T03:00:00Z44m

Haunted by past mistakes, Hamilton embarks on a journey to correct an error in his reporting and identifies the origin of an international toad venom smoking phenomenon.

From X-ray crystallography to vesicular dopamine release, Hamilton travels the country visiting meth labs in order to understand the process behind a great American folk art.

Hamilton traces the multibillion year history of nitrous oxide on Earth and follows the strangest noble gas to the Czech Republic.

After revealing a scientific mystery around Tramadol-addicted cows in Central Africa, Hamilton follows a Gabonese opiate addict to a psychedelic ritual.

Succumbing to viewer requests, Hamilton journeys to South America to understand the legend of Bufotenine, the world's oldest psychedelic.

Season Finale

2021-02-09T03:00:00Z

3x06 Ultra LSD

Season Finale

3x06 Ultra LSD

  • 2021-02-09T03:00:00Z44m

With the precise structure of LSD's molecular target identified, Hamilton discusses the new era of psychedelic research and meets pioneers of the field.

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