A professional extermination team, the Nozama Peston Service, are deployed to hunt flesh-eating organisms called Amazons, which are slowly appearing across the city.
With a green Amazon entering the fray, the red Amazon - Alpha - aims to capture him. The Nozama Peston Service are tasked with hunting down a Dragonfly Amazon - one of their own team.
With the mass awakening of Amazons, the Nozama Pharmacy executives hold a board meeting. The Nozama Peston Service are sent to an apartment building to deal with an Amazon infestation.
Haruka joins forces with the Nozama Peston Service, who are trapped inside an apartment complex, surrounded by 183 Ant Amazons.
Asked to leave the Nozama Peston Service, and fearing being caged once more at home, Haruka runs away. A disappearing Amazon signal sends the remaining Nozama Peston Service members out on the hunt.
The Nozama Peston Service are able to recover an undissolved Amazon, which they deliver to Nozama Pharmaceuticals for research. Haruka struggles to find his own reason to fight, and so turns to Jin for answers.
A freak accident reported on the public news matches all the traits of a recent Amazon attack. The Nozama Peston Service heads to the crime scene to investigate.
When the Shrike Amazon escapes, the Nozama Peston Service goes in pursuit. But all is not as it appears in this murder case.
A number of Amazons have been awakening in one specific area - a closed down restaurant. The Nozama Peston Service go undercover to investigate. Meanwhile, Tachibana's plans come to fruition.
Narrowly escaping death at the hands of the newest Amazon, Sigma, Jin meets with the Nozama Peston Service to trade information and reveal a shocking secret.
Haruka is fatally wounded following his fight with Sigma, and Operation Tlaloc is nigh. Who will walk away from the killing day?
A storm is coming, and Jin moves to ensure that Operation Tlaloc is carried out. The Nozama Peston Service quickly find themselves overrun by a mass awakening of Amazons.
Three weeks have passed since Operation Tlaloc. As Nozama Pharmaceuticals continues to clean up the wreckage, the surveillance team goes missing...
A group of youths, under the moniker 'Team X' are hunting down Amazons. Leading the charge is a mysterious blue Amazon, Neo.
Chihiro, who was brought back to 4C, wants to exterminate the Amazons with Iyu. In the battle with no emotions and only pain, Chihiro transforms to protect someone for the first time.
Haruka Mizusawa, Kamen Rider Amazon Omega, heads back into town. Returning from exile after Operation Tlaloc. He has found a new target in Iyu, who is a Sigma Type Amazon.
Chihiro wishes to act more human. He leaves the 4C compound to spend time with Iyu. Makoto Shido begins investigating an important incident, and encounters a person who he never thought he'd meet again…
As Mamoru (Mole Amazon) confronts his comrades from the past, Mizuki Mizusawa again encounters Haruka Mizusawa (Kamen Rider Amazon Omega). Can the 5 years which has separated them be filled?
Haruka Misuzawa (Kamen Rider Amazon Omega) continues his search for Mamoru, the Mole Amazon. HE soon encounters the extermination team, including Chihiro (Kamen Rider Amazon Neo) and Iyu, the Crow Amazon. Meanwhile, something strange is happening at the hospital where Emiri was admitted.
As Jin finally met Chihiro, all past events prior to Chihiro's birth and what came after Tlaloc alongside Jin and Haruka's war had finally been revealed.