Twenty-two years after the disappearance of his father, Wataru Kurenai lives in an infamous "haunted house" where he is destined as Kamen Rider Kiva to fight life-draining monsters called Fangires, the very race his father fought years ago before his disappearance. Wataru must also deal with Kamen Rider Ixa who is part of an organization seeking to destroy the Fangire menace, as well as the Fangires' own Rider, Kamen Rider Saga. The story is split between the actions of Wataru in the present (2008–09) and his father Otoya in the past (1986–87), slowly revealing the link between the Fangire Race and Kiva.
The characters of Kamen Rider Kiva are spread throughout two time periods, each related to one another. There are the actions of Otoya Kurenai and the Fangire Hunter Yuri Aso with the Wolfen Jiro in the year 1986 with the first Ixa Ver.I that result in the various Fangires that persist to the current day, in 2008, with Otoya's son Wataru (as Kamen Rider Kiva) along and Keisuke Nago (as Kamen Rider Ixa Ver.X) and Yuri's daughter Megumi (also a Fangire Hunter), dealing with the Fangires to prevent deaths.