Emerging from a mysterious laboratory in Japari Park, a human child encounters two Friends, Serval and Caracal, who name her Kyururu. After finding a sketchbook where Kyururu emerged from, the group travel to the locations drawn in the sketchbook in order to find Kyururu's home. Along the way, they come across Indian Spot-Billed Duck, who leads them to the second location in Kyururu's book, a monorail station. When a Cerulean appears, Indian Spot-Billed Duck distracts it while the others head onto the monorail before another mysterious Friend defeats the Cerulean.
Stopping off at Azea Park to search for the next location in Kyururu's sketchbook, the group meet Giant Panda, who falls asleep while giving them directions, and Red Panda, who attempts to guide them without knowing where it actually is. Despite this, the group do eventually find the location of a playground, which Kyururu and the others help put back together. When Ceruleans show up to destroy the playground, Giant Panda gets upset and beats them all single-handedly. After learning that some other Friends were searching for a human, Kyururu and the others set off towards their next destination, the Marine Life Park.
The girls arrive at the Marine Life Park and meet Bottlenose Dolphin and California Sea Lion, who take them on a boat to a stadium submerged underwater. After showing Kyururu the stadium, Dolphin and Sea Lion refuse to take everyone back to land unless they give them a reward. Recalling something about the stadium, Kyururu uses objects on the boat to teach Dolphin and Sea Lion new tricks to perform, with the applause they receive convincing them to take everyone back. Meanwhile, a Giant Armadillo and Giant Pangolin who are following Kyururu's trail report to a mysterious figure.
With a gap in the track preventing the monorail from going any further, Kyururu and the others are guided by another Lucky Beast through South Maerica Park to the next location in Kyururu's book. There, they come across Aardwolf, who has come to meet with Campo Flicker to find a new place to live.
The girls find themselves come across some feuding crocodilians and leopards, who have a hard time believing that Kyururu is a human. Their leader, Western Lowland Gorilla, offers to let Kyururu meet a human she knows on the condition that she pretend to be scary in order to stop her underlings fighting with each other. However, this only leads the two factions to fight over Kyururu, as they believe humans have the ability to make animals their servants. To remedy the situation, Kyururu makes a paper wrestling game for everyone to settle their disputes with. Just then, Kyururu is attacked by an aggressive Friend, but is saved by the arrival of another human; Kaban.
After taking Kyururu and the others back to her lab, Kaban, who has been researching with the owls, explains that the tiger they encountered was a Beast, an animal who didn't become a Friend upon encountering Sandstar.
In the desert, Kyururu's group comes across a cheetah who is challenged to a race by a pronghorn, with Serval deciding to participate.
Kyururu's group arrive at the live stage and meet up with Margay, who has them take part in a play for the opening act of PPP's next concert. Following a bad rehearsal, PPP decide to cancel the play, leaving Margay downhearted. However, when the PPP gets held up upon being pestered by Alma and Sen, Kyururu and the others put on the play themselves, which proves to be a hit despite the appearance of an actual Cerulean, buying enough time for PPP to take the stage. Following the concert, Kyururu gets captured by Alma and Sen, who take them to see a certain Friend.
Alma and Sen deliver Kyururu to their client, Domestic Dog, who has been waiting a long time to meet a human and takes Kyururu back to a set of human houses. When the others catch up to them and assume Kyururu had found her home, Caracal argues with her and starts making her way back home. Upon learning that a Beast is nearby, Kyururu goes off to try and warn Serval and Caracal, only to come up against the Beast herself. Dog gets injured protecting Kyururu, Serval and Caracal, who had realized her folly, return to fight off the Beast, after which Dog encourages Kyururu to continue travelling with her friends.
While searching for his sketchbook, Kyururu finds it in the hands of a western parotia and a greater lophorina, who question his motive for finding his house. Afterwards, the gang meet a passenger pigeon, who takes them to a hotel run by a bat-eared fox, a domestic pig and an Okinawan habu. Meanwhile, Kaban discovers that the recent appearance of Ceruleans resembling Friends has something to do with Kyururu's sketchbook.
While sinking into the ocean, Kyururu has a dream where she once again encounters Parotia and Lophornia, who warn her of an impending crisis. She is then rescued by Dolphin and Sea Lion, who inform everyone about the Ceruleans emerging from Kyururu's drawings. Just then, a giant boat-shaped Cerulean attacks the hotel, causing Ceruleum to come into contact with the drawing Kyururu gave Pigeon and spawn Ceruleans of all the Friends drawn on it. As Kyururu desperately tries to find Pigeon, Kaban arrives with all the other Friends in tow to help fight off their Cerulean doppelgangers.