Arsenal host Burnley while Manchester United's are at Wolves.
Wolves lost 3-0 to United in the reverse fixture before Christmas, with manager Mick McCarthy criticised for fielding an under-strength team. With home advantage, McCarthy will plot a repeat of the shock win by Wolves when they last hosted then-league leaders United in the Premier League in 2004.
Burnley make their first visit to Arsenal in the top flight since 1975. The sides drew 1-1 at Turf Moor earlier in the season, but Burnley's away form has been as wretched as Arsenal's home form has been excellent. The Gunners are hopeful that a relatively easy run-in will keep them in the hunt for the league title, and winning fixtures like this one are essential if they are to challenge for silverware.
