Years after his victory at Megalonia, Joe has become a completely different man, going from one underground ring to another, now fighting as the wandering boxer Nomad.
Joe gets his motorcycle stolen by a boy named Mio and ends up at a settlement for immigrants where he runs into Chief again.
Joe helps Chief get ready to fight in the upcoming tournament while dealing with is own demons.
Chief fights in the last match of the tournament. Will he be victorious?
Joe heads back home to face his past.
Sachio ends up injuring a Megalo-boxer after they caused trouble at Bonjiri's shop. In retaliation, the Megalo-boxer comes back and trashes the place and steals the deed to the shop.
Liu finds out Joe is back in town and asks him to be his sparring partner. Mac Rosario had once lost everything, but made a miraculous comeback as the local hero.
Mac and Liu face off in the ring finally. Maya goes to talk to Sakuma after she finds Mac acting strange.
Joe continues to try to rebuild Gym Nowhere and Yukiko has some questions for Sakuma about BES.
The executives don't like Yukiko's decision to possibly end the company's partnership with ROSCO. Meanwhile, Joe and Sachio settle things once and for all.
It's decided that Mac and Joe will get into the ring together, but Mac finds out something shocking from Maya...
Mac falls into despair when he finds out the truth and encounters a familiar face from his past.
Joe and Mac head into the ring to have their legendary match.