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The Corona, a deep space salvage freighter, is out on a mission when it encounters a distress signal and responds to it.
A lab technician Nobuo Tanaka, battling the flu, mistakes some experimental pills for cold pills and swallows one. The pills are part of a biological weapon program, reacting to the flu shot already in his body.
In a walled city perpetually at war, everyone's livelihood depends upon maintaining and firing the enormous cannons that make up most of the city.