When former fashion model Maddie Hayes goes broke and finds that one of her few remaining assets is ownership of the Blue Moon Detective Agency, she is tempted to liquidate it until she meets the quirky employees and gets involved in their even quirkier cases.
Dave's older brother shows up unexpectedly, flashing a big roll of money and determined to impress a bemused Maddie, unaware that he's pursued by a drug dealer who wants his money back.
A mysterious veiled woman asks Dave and Maddie to find the man who disfigured her twenty years ago on her wedding day-so she can marry him.
Maddie learns through the near-suicide of a friend where her embezzling accountant has fled to and immediately flies after him, determined to get her money back.
Dave and Maddie each dream their own solutions to an unsolved 1946 murder case after hearing the story while finishing an investigation.
Maddie bets David that he can't act like a mature responsible professional for one full week while they deliver ransom money for the mother of a kidnapped concert pianist.
Maddie fears David's old flame is using him when she returns and asks him for help with a bad marriage.
Dave and Maddie argue over whether to help a young woman who claims to be a leprechaun find the pot of gold she insists her father has hidden for her in Los Angeles.
Maddie becomes obsessed by the portrait done of her by an artist she never knew and who killed himself upon completing it.
Dave busies himself finding an important phone index for a hapless young executive while Maddie mulls over an offer to sell the agency to a competitor.
Ms. Dipesto finds a baby left in her apartment by a woman named Mary fleeing from the hit men who killed her husband, and Dave and Maddie quarrel over using the agency phones as a "Santa hot line."
Dave and Maddie compete to fulfill their client's unusual request: find him a possible mate fitting his very specific requirements.
A restless Ms. Dipesto gets a chance for danger and excitement when she gets a piece of paper from a mysterious man while attending a ball in Dave and Maddie's place.
Dave and Maddie agree to "corpse-sit" for an escape artist's widow, who believes her dead husband's threats to come back and get even with her.
Maddie worries about her parents' strange behavior, so Dave tails her father to see if he's having an affair.
A sick old man asks Dave and Maddie to be the "expert" witnesses at his murder.
Dave uses information passed on to him from a prostitute with an important client who talks in his sleep to solve several big cases.
A depressed man hires a hit man to kill him after his wife dies, then desperately seeks Dave and Maddie's help to call him off when he sees his supposedly dead wife alive.