Like most proud parents, Ray and Jenny Moyer are ecstatic when their daughter Daphne is born. But soon after Ray and Jenny bring Daphne home from the hospital, she becomes irritable, has trouble nursing and stops gaining weight. What could be wrong?
Mary and Rich Jordan are excited about the arrival of their adopted twin sons, Joey and Patrick, but they notice early on that Joey seems to drink excessively and then projectile vomits. By age two he is up all night demanding fluids and stops growing.
Parents Ed and Jane try to figure out why their son, Alex, is so unsteady on his feet, and why he has recurring sinus infections. A 31-year-old woman begins gaining weight and complaining of oily skin, hair loss, body cramps, and irritable bowel syndrome.
Natalie and Steve Bonfig are overjoyed after their second daughter Nicole is born. However, their worst fears are realized when they discover that Nicole is not only dealing with a serious heart condition, but has also stopped growing and gaining weight.
Soon after Maia Cooper is born she falls critically ill from whooping cough. Months after recovering from this illness her parents notice something troubling - Maia's hair appears abnormally brittle and she is slow in reaching developmental milestones.
Since childhood, Scott Gober battled an array of symptoms - severe joint pain, strange rashes, and an inability to sweat. First diagnosed with juvenile rheumatoid arthritis, his pain continued for years and doctors are still searching for the cause.
Roman Magana was just a baby when his parents noticed that his head was constantly tilting to one side. To make matters worse, his eye rolls back into his head when he looks up. Could both of these peculiar symptoms stem from the same condition?
Jackie Spar is an outgoing, active teenager who is full of promise until mysterious pains take over her entire body. The joint problems become so bad that Jackie must drop out of high school. Will doctors find out what is causing her malady in time?
A man in his late 30s experiences a constant, painful burning sensation in his chest, making breathing difficult, but an initial trip to the ER reveals nothing.
A person with Tourette's syndrome who endures thousands of violent tics a day; a father and son whose legs face backward. Also: sleep-eating; a parasitic twin; a teenage hunchback; Williams syndrome.