The sixth and final season of Private Practice premiered on September 25, 2012, with a limited run of thirteen episodes. Private Practice was renewed for a sixth season on May 11, 2012.
In a recent interview, Shonda Rhimes stated that this season will feature: "a death, some babies, a likely return of a favorite and there could possibly be a wedding" with the rumored possibility of a musical episode and return of ex-cast member Audra McDonald. On October 19, 2012, after months of speculation, series creator Shonda Rhimes announced that the sixth season would be the final season of the show. It was confirmed, that production wrapped on December 7, 2012, and the final episode had been taped.
Addison settles into her new life after making a decision between Jake and Sam; Violet fears the worst when Pete doesn't show up to his preliminary court hearing; and Charlotte swears Cooper to secrecy when she receives shocking news. Meanwhile, Amelia celebrates one year of sobriety and Sheldon rekindles a romance with his ex-wife.
The doctors join together for a celebration at Addison's house and to reminisce about the past. Meanwhile, Sheldon counsels a suicidal patient who comes forward with a shocking confession.
After hearing a patient's chilling confession, Violet turns to Sheldon for advice. Meanwhile, Addison tries to keep her grief a secret, Cooper and Charlotte adapt to their new reality and Sam confronts Sheldon about his denial.
Sheldon fears the worst when a little girl goes missing from the ER; Addison and Jake have a disagreement about one of his patients; and a new doctor joins the team at Saint Ambrose. Meanwhile, Stephanie questions Sam about his past with Addison.
A reality show centered around Sam sheds some light on issues in his colleagues' personal lives. Meanwhile, Sam's mother seeks his help after her boss falls ill; and the search continues for a girl who went missing from St. Ambros.
In this Addison-centric episode, her role as a parent is challenged when Henry's biological mother reappears and asks to be more involved in her young son's life. Meanwhile Addison reconnects with her mentor, who shares a very painful secret.
Upon hearing that he must meet with Henry's social worker during a home visit, Jake fears that an incident in his past will come to light. Meanwhile, Addison becomes skeptical of Jake's needy patient and James continues to pursue Amelia.
In an episode told from Cooper's point of view, we follow him from the moment of conception through a nasty fight with Charlotte, which inadvertently threatens the lives of their triplets. Meanwhile, Violet comforts a friend who is being advised to take her partner off life-support.
During a dark moment in his life, Sheldon finds happiness with a new woman. Meanwhile, he becomes increasingly suspicious about his patient Nick's involvement in Sarah's disappearance.
Charlotte stresses the doctors out when she continues to run Saint Ambrose Hospital from her doctor-ordered bed rest. Meanwhile, scared that Charlotte might never leave the hospital, Mason begins acting out in school.
Amelia, now sober for more than a year and on the mend emotionally, goes on a series of disastrous blind dates set up by the other doctors at the practice. After vowing to be alone indefinitely, she teams up with James on a medical procedure, which leads to dinner — and the dinner leads to something completely unexpected
Addison attends Henry’s court date and realizes that the judge still has some concerns about Jake’s past, Sheldon introduces Miranda to his friends, and Cooper’s efforts to secure a dream house are put on hold when Charlotte goes into labor.
Naomi returns to stand by Addison’s side on her wedding day, Cooper struggles with the hardships of being a stay-at-home father, and Violet begins a new project close to her heart, on the Series Finale of "Private Practice."