Pushing Daisies centers on the life of Ned, a pie-maker gifted with the mysterious ability to bring dead things back to life by touching them. There are some conditions to this somewhat unusual talent. Ned quickly learns that if something is revived for more than exactly one minute, something of similar "life value" in the vicinity drops dead, as a form of balance. Additionally, if he touches the revived person or thing a second time, it falls dead again, this time permanently.
Ned works in a pie store and seems to lead a perfectly normal life. This, however, is far from the truth. Ned can, through the touch of his hand, wake people from the dead. He decides to use this ability of his to solve crimes, but this appears to be much more difficult than it sounds, when he gives life to his childhood crush, and decides to let keep living.
Ned, Emerson and Chuck visit the morgue to inspect the body of a victim of a car accident, a 45 year old man who specialized in automobile safety. The police is offering a reward to anyone who can find the killer and Emerson wants answers to be able to get the reward.
Chuck holds true to the threat she made in the pilot by baking anti-depressants into her aunt's food, in the form of Ned's pies. Olive delivers one to them and stumbles onto Chuck's secret. Now that she has dirt on Chuck - that her aunts think she's dead - will Olive use it against her to get Ned?
Emerson, Ned and Chuck are hired to prove that a pilot was murdered, rather than committing suicide, but soon become involved in a case of stolen jewelery and an escaped prisoner.
In this Halloween episode, Emerson and Olive track down "the ghost" who's been killing the jockeys at the old race arena where Olive used to race as a former jockey herself. With help from Ned and Chuck, they try to solve the big mystery.
Ned, Chuck, Emerson and Olive tackle a murder mystery involving a man who was murdered over a dog and claims to have been killed by his wife. Problem is, he's a polygamist with four wives.
Ned, Emerson, and Chuck's next case involves an olfactory assistant who was killed when her scratch-'n'-sniff book combusted.
Emerson, Ned and Chuck investigate the death of Tony DiNapoli, who appears to have been strangled by a woman. Meanwhile, business at the Pie Hole plummets when a new candy store opens in town. Alfredo Aldarisio returns and continues to pursue an oblivious Olive who, herself, still pines for affection from the Pie Maker.
Chuck learns the most shocking secret of her life and refuses to forgive Ned. In order to take the Pie Maker's mind off of Chuck, Emerson gets him to solve the mystery of a man killing life insurance agents and hiding them in snow banks. Oscar Vibenius returns to investigate why Chuck has an unique smell. Meanwhile, the aunts' antidepressant-laced pies begin to show some hallucinogenic effects.