Being a single mom in today's world is a daunting task. For Reba Hart (Reba McEntire), parenthood encompasses not only watching over three kids, but also keeping an eye on a son-in-law, a granddaughter, an ex-husband, and an ex-husband's neurotic wife. 'Reba' began with the Hart family in the midst of a divorce as Texas soccer mom Reba watched her white-picket-fenced world collapse before her very eyes. Her dentist husband, Brock(Christopher Rich), left her after what she thought was 20 happy years of marriage for his impossibly perky and unfortunately pregnant dental hygienist, Barbra Jean (Melissa Peterman). The cherry on top of this bitter sundae was the pregnancy of Reba's then 17-year-old daughter Cheyenne (JoAnna Garcia) and her decision to marry her high school football star boyfriend, Van (Steve Howey). Rounding out the happy brood is teenage Kyra(Scarlett Pomers), who continues to greet puberty with venom, and son Jake (Mitch Holleman).
Struggling to remain sober, Cheyenne starts taking pills that will make her violently ill if she drinks alcohol. When Reba throws a party for her real estate clients, Van and Cheyenne go to great lengths to try and stop Reba from drinking after she accidentally takes one of Cheyenne's pills, thinking it's a vitamin. Meanwhile, ex-smokers Brock and Barbra Jean lecture Kyra and Jake on the dangers of smoking, but that doesn't stop Brock from secretly lighting up.
Barbra Jean takes it upon herself to find the perfect man for Reba by signing her up at an online dating service, but she later regrets her decision when Reba begins dating a mystery man and doesn't have as much time for the her or the family. As a result, Cheyenne and Van realize how much work it takes to care for their daughter without Reba's help, and Barbra Jean and Brock, who wants to make sure he's better looking than Reba's new boyfriend, decide to check out their competition.
After watching her fiercest competitor make a killing in the real estate market, Reba decides it's time to start investing. However, she can't do it alone with her bad credit, so Cheyenne suggests that Reba and Van team up. Later, when Reba finds out that Van went behind her back and purchased a home "as is," without any inspections, she wants out of the partnership. Meanwhile, Barbra Jean is feeling neglected by Brock and finds companionship from an unlikely source - the operator from her car's navigation system.
The Hart family becomes concerned when Van continuosly sits at home watching football instead of attending church. After many failed attempts in talking him into going, Reba and Barbra Jean confront him on his refusal. Van confesses that he no longer believes in God, greatly disappointing Reba and Barbra Jean. To try and bring Van to God, they drag him to Reverend Parks who tells Reba and Barbra Jean that he can't help the people who don't want help. Reba in a heated discussion finally admits to the Reverend that she too has had her doubts.
When Reba and Jake take in a stray dog that survived Hurricane Katrina, Van and Cheyenne invite the owners to stay at the house until they can get back on their feet. However, the Harts are in for a big surprise when it turns out there are 18 people in the displaced family. Meanwhile, Barbra Jean heads up the "Save the Dog" campaign and turns her house into a shelter for lost pets, leaving dog-hating Brock more than annoyed.
Reba is beyond disappointed when her plans for a fright-filled Halloween fall through because everyone in the family has other plans. Meanwhile, Van's green-eyed monster comes out when Cheyenne starts spending an inordinate amount of time with her handsome sponsor, Frank
Realizing that his wife, Barbra Jean (who was pregnant in real life at the time this episode was taped), has taken up eating as a hobby and gained quite a bit of weight as a result, Brock consults Reba on how best to handle the delicate situation. Ultimately, Cheyenne is the one who confronts Barbra Jean about her food addiction, suggesting that she and Reba go on a diet with her.
When Cheyenne declines Brock's offer to intern at his dental office, the family finds out she no longer wants to become a dentist. Instead she plans to devote her life to helping people. Reba, Van and Brock are upset by this and visit the senior center where Cheynne has been volunteering and discover that she's been "helping" by giving the women makeovers. Meanwhile, Barbra Jean's attempt to get picked for jury duty backfires after she annoys the judge.
After a miscommunication sends Barbra Jean (who does not appear in the episode) to her brother Buzzard's house in Lubbock for Thanksgiving, Buzzard mistakenly ends up on Reba's doorstep for the holiday. The family soon realizes they may have traded crazy Barbra Jean for her even crazier brother, who believes that Reba has been sending him love letters signed "Peaches" and that Brock is "the dirtbag who's trying to take my sister to hell with him."
After observing their constant bickering in the real estate office, Reba and Van's boss insists they see the company's occupational therapist to work things out. Meanwhile, Brock and Barbra Jean consult a sleep doctor who suggests they videotape themselves in bed to find out why Brock is waking up exhausted and achy every morning.
When Brock decides to camp out at Reba's house while Barbra Jean is away in St. Louis, Reba gets fed up and tries to kick him out. However, Brock is diagnosed with kidney stones and doesn't want to be left alone, so Reba ends up caring for him. Meanwhile, Cheyenne volunteers at a homeless shelter, but is disappointed when she is assigned the unglamorous task of doing dishes in the kitchen.
Reba doesn't approve of Barbra Jean's method of disciplining Henry. However, when Jake lies and blames Henry for breaking Reba's lamp, Reba is forced to
apologize for criticizing Barbra Jean's parenting skills. Meanwhile, Brock and Van are mistaken for a gay couple when they spend their "guy time" at a day spa.
After Brock and Barbra Jean get audited, Brock informs Reba that the IRS is going to audit the last five years of their marriage. Later, Brock makes Reba nervous when she discovers that he has a few secrets he doesn't want the IRS to find out about.
Meanwhile, Cheyenne makes Van take part in her sociology project about a man's perspective on marriage, but she certainly wasn't anticipating all the attention he would receive from the women in her class.
In the wake of Barbra Jean spilling the beans to the IRS that Reba and Brock owe $75,000 in back taxes, an embarrassed Brock decides the only way he can pay off the debt is by selling his house and moving to Las Vegas. When Van hears the news, he aims to become Brock's broker and a devastated Barbra Jean tries to change Brock's mind.
When Reba learns that Van is in charge of the family budget and has Cheyenne documenting all her purchases in an expense journal, she advises him to treat Cheyenne more as an equal. Unfortunately, Van decides the best solution is to start giving Cheyenne a weekly allowance for her household duties, which obviously doesn't sit well with his wife. Meanwhile, Barbra Jean discovers that Jake has started a lucrative business selling soda - against school policy - to his classmates.
Dr. Jack Morgan moves back to town and tries to rekindle his relationship with Reba, However, Jack reveals to a shocked Reba that he is technically still married. Reaching the startling conclusion that she has unknowingly become the "Barbra Jean" in her relationship, Reba goes to an unlikely source for advice - Brock.
In an effort to save Brock and Barbra Jean from losing their home, Reba and Van buy their house and rent it out to them. Barbra Jean doesn't like the idea of Reba being her landlady, so when she sprains her ankle in the house, she decides to file a lawsuit against Reba.
After the family makes fun of Reba's poor eyesight, she secretly gets laser eye surgery, which leaves her temporarily blind. Barbra Jean insists on helping Reba post-surgery while the rest of the family is away. Later, thinking she is talking to Cheynne, Reba badmouths Barbra Jean, only to find out she's been talking to Barbra Jean the whole time. Overwhelmed with guilt for the hurtful things she said, and with Brock's help, Reba finally tells Barbra Jean how thankful she is for their friendship.
Reba is worried when she and Brock must attend an anger management therapy session that was mandated by the court during their divorce. Cheyenne and Van are required to be present as well, and Reba fears things have gone from bad to worse when everyone starts arguing in front of the therapist. Later, Barbra Jean crashes the session and the five adults end up telling the therapist about the crazy things they have done to each other over the years.
When Barbra Jean takes up selling insurance, she wants Reba to be her first client. After Reba's physical shows that she has high blood pressure, she finds out she's at risk to lose her old insurance policy. Meanwhile, Van seeks out Brock's advice in coming up with a unique anniversary present for Cheyenne.
Cheyenne gets overwhelmed planning her second wedding to Van when Reba and Barbra Jean won't stop putting their two cents in. Later, Van and Cheyenne have an argument and decide to call off the ceremony, leaving Brock and Barbra Jean with the opportunity to renew their own vows.
After collapsing at Van and Cheyenne's non-wedding, Reba is rushed to the hospital. The family is panicked about her health, but she only wants to focus on helping Van and Cheyenne resolve their relationship troubles. Meanwhile, Barbra Jean tries to help Reba feel better, but only makes Reba's blood pressure continue to climb.