As Kenshin, Sanosuke, and Yumi make their way to the top of the Inferno Arena, Kenshin thinks about his past, and what awaits him next, the entire way up to where Shishio himself is waiting. However, Kenshin is ready and prepared to the final battle with the manslayer known as Shishio. Upon reaching the door at the top, Yumi pulls the switch to open the door. Shishio is standing in the middle of the arena, and Houji is also there. After a few opening words with Kenshin and Shishio, Shishio promises Yumi that the battle will end quickly. He gives Yumi a kiss, walks off, and the fight between the two manslayers begins! Shishio shows off his first Secret Sword attack, the Homura Dama. He then bites a chunk off of Kenshin's shoulder.