Eccentric genius, Walter O'Brien and his team of brilliant misfits comprise the last line of defense against complex, high-tech threats of the modern age. As Homeland Security's new think tank, O'Brien's 'Scorpion' team includes Toby Curtis, an expert behaviorist who can read anyone; Happy Quinn, a mechanical prodigy; and Sylvester Dodd, a statistics guru. Pooling their extensive technological knowledge to solve mind-boggling predicaments amazes federal agent Cabe Gallo, who shares a harrowing history with O'Brien. However, while this socially awkward group is comfortable with each other's humor and quirks, life outside their circle confounds them, so they rely on Paige Dineen, who has a young, gifted son, to translate the world for them, while also helping each other learn how to fit in.
When a crisis at LAX leaves dozens of airplanes unable to land, the government enlists a team of misfit geniuses to save the day.
The Governor calls on Team Scorpion when his daughter is mysteriously "bio-hacked" with a deadly virus and has only 24 hours to live. Meanwhile, the case takes on a deeper significance for Walter after he receives a letter regarding his sister.
After Team Scorpion fails a military training mission, they are determined to prove their worth to Cabe and Homeland Security when a bomber threatens to take out the internet infrastructure of the entire Southwest.
Against Cabe's advice, Team Scorpion heads to Las Vegas for a simple casino job, but a robbery leads to Walter's arrest and the rest of the team is left to clear his name.
To fix a Los Angeles nuclear reactor that's on the verge of a cataclysmic meltdown, Walter and the team must reluctantly enlist the help of a troubled former member.
Team Scorpion must pass a mandated psych evaluation or face being disbanded after they're accused of destroying a priceless work of art in an attempt to protect an art exhibit. Meanwhile, Paige enlists the help of the team when Ralph is reluctant to go to his school's Halloween party.
A case gets personal for Team Scorpion when three convicts break out of prison and one of them is a brilliant hacker who was forced to help the others steal billions online. Meanwhile, Paige must manage Ralph's expectations when his father returns.
Team Scorpion enlists the help of a musician who created a controversial algorithm that generates hit songs to help find the murderer of a music blogger. Meanwhile, Drew asks Walter to help him connect with his son.
Team Scorpion must help protect Cabe's ex-wife after she uncovers evidence that suggests foul play in the death of a prominent congressman.
When a military plane is shot down in Bosnia, Team Scorpion must help recover its stealth technology before it falls into enemy hands. Meanwhile, Walter's sister takes a break from her MS treatment and spends time at the garage with Sylvester.
When Sylvester accidentally triggers an explosive device during an investigation, Team Scorpion must focus on finding who's responsible even while their friend's life hangs in the balance.
As Christmas approaches, Team Scorpion races to find a way to save a young boy's life after he gets trapped in a beachside cave and drowning is imminent.
Team Scorpion must help Ralph when the FBI questions him after his dark web game play inadvertently reveals the location of a CIA safe house and results in the murder of CIA operatives.
Team Scorpion is tasked with uncovering a mole inside the CIA whose judgment is clouded by matters of the heart and is being coerced into stealing deadly chemicals. Also, in preparation for the case, Paige gives Walter a flirting lesson.
Team Scorpion must jog the memory of an injured former Secret Service agent who is their only hope of preventing weapons of mass destruction being launched from a secret U.S. nuclear silo. Meanwhile, Paige is torn when Drew suggests that moving to Maine might be better for Ralph.
Team Scorpion goes undercover on a cruise ship to locate and disable deadly stolen rockets. Meanwhile, as Valentine's Day approaches, Toby and Happy help Ralph, who is in the throes of his first crush.
A tech billionaire hires Team Scorpion to rescue his kidnapped daughter. Meanwhile, some feelings get hurt when Walter gives an interview and fails to acknowledge the other members of the team.
When a conflict in Eastern Europe threatens to escalate, Team Scorpion is called on to help facilitate secret peace talks to prevent World War III.
While on a mission to save lost hikers, Team Scorpion’s helicopter crashes, igniting a massive wildfire that quickly closes in on them. Also, Sylvester must help their injured pilot who is unable to make it to safer ground.
To protect a key witness who is en route to testifying against a deadly drug cartel, Team Scorpion takes her on the run, with the cartel hot on their heels.
Walter finally learns Cabe’s long-kept secret regarding the Baghdad mission, and it threatens to tear Team Scorpion apart forever. Also, Paige’s world is rocked when Ralph puts his life in danger to help the team.