Season five finds the Gallaghers dealing with both the upside and downside of personal and urban renewal. As their neighborhood begins a move towards gentrifying, the Gallagher clan begins to reconcile their chaotic past in the hopes of building a better future.
Fiona juggles her job and a crush. Lip heads back home.
Sheila gets an offer to buy her home. Plus, Fiona is off house arrest!
Frank enlists Carl to scare off the lesbians. Debbie throws a wild party.
Frank retraces the path of an epic bender. Fiona and Gus head to city hall.
Fiona's plans to announce her marriage unravel. Mickey asks for Lip's help.
Fiona is thrown into chaos by the return of Jimmy. Ian takes Mickey's baby.
Ian begins to regain some of his senses - and finds himself under a mandatory hold at the psych ward. Meanwhile, Sammi is forced to take drastic measures to teach Frank a lesson. Plus, Fiona makes a decision regarding her potential romantic futures with Jimmy and/or Gus, Lip learns that his tuition is short twelve grand, Carl seizes an opportunity to make Chuckie his slave, and after V moves out, Svetlana moves in with Kev in exchange for the performance of some odd 'wifely duties.'
Fiona is confused by the status of her relationship when Gus announces he's leaving to go on tour. Meanwhile, Carl is asked by his boss to run drugs to Indiana; Frank sees a way to get revenge on Sammi by using Chuckie as the mule and having him busted; and Lip, still in need of tuition money, convinces Kev to come to the dorms and sell drugs. Plus, as Ian refuses to accept his bipolar diagnosis, Debbie is tasked with minding his new meds
Frank has a check-up with his uptight doctor, Bianca, who's cracking up after getting a terminal cancer diagnosis. Discovering she hasn't truly 'lived,' he agrees to be her tour guide to the seedier side of life. Meanwhile, Fiona preps an uncooperative Carl for his sentencing hearing. Plus, Lip sleeps with a professor on the assumption he's only days away from being kicked out, Ian realizes it's time to get back on his meds and Kev finds himself enjoying college life as campus 'rapewalker.'
Frank is having a ball with Bianca, his new sick friend and formerly uptight doctor. But when Bianca thinks Frank might be developing feelings for her she kicks him to the curb. Frank, however, returns to put up a fight.
Frank grows concerned as Bianca's behavior becomes increasingly more erratic and dangerous - but he'll do just about anything to show her a great time.
Fiona reunites with Gus after he returns from his tour, but she struggles with the fact that her feelings for Sean have turned into love. In Costa Rica, Frank has love struggles of his own while he works to keep Bianca happy.