Starhunter follows the exploits of the crew of the spaceship Trans Utopian (The Tulip) , a former luxury liner that has been refitted to serve a bounty-hunting crew. Leading the crew during the first season is Dante Montana (Michael Paré), who became a bounty hunter in order to search for his son, Travis, who was abducted ten years earlier by a group of Raiders. During the raid, Dante's wife, Penny, was killed. The Raiders are a group of genetically enhanced former-soldiers who were rendered sterile, and must abduct children to increase their numbers. Percy Montana (Tanya Allen) is Dante's niece, and the ship's engineer. Dante adopted her when her parents were killed during the raid where Dante lost his wife and son. Rounding out the crew is Lucrecia Scott (Claudette Roche). Luc, a former marine, was placed aboard the ship by Rudolpho DeLuna (Stephen Marcus), the ship's owner, to look out for his interests.
Dante is reunited with MacDuff, an old friend who is dying from cancer. Luc's father, Darius, asks her to capture a geneticist who may hold the key to an alien gene known as ""The Divinity Cluster"".
Against Dante's and Luc's warnings, Percy becomes friends with one of a pair of cousins that The Tulip is transporting to an automated prison on Mercury.
While hunting a pair of con artists on Mars, Dante and Luc encounter a Raider with a boy who may be Dante's kidnapped son. Percy becomes trapped in Dante's VR device, which simulates his dead wife, Penny.
After Dante and Luc capture Petrakis, an escaped prisoner who hijacked a luxury yacht, the Tulip is commandeered by Special Forces. They are transporting Ire, a girl with amazing powers who may be infected with a deadly virus.
On a mission to a mining facility on Pluto, Dante and Luc attempt to capture Novak, a war criminal responsible for sacrificing thousands to the Divinity Cluster. Percy and Caravaggio deal with a holographic computer virus named ""Billy Ray"", who is wreaking havoc aboard The Tulip.
Dante arrests a doctor and her son, unaware that she has a device that can control his mind.
While transporting Etienne to a prison, the Tulip receives a distress call from Dr. Devon. Devon is pursued by Raiders after freeing his son, Ryan, from an Orchard medical research facility.
Rudolpho instructs the crew to pick up a murder suspect who turns out to be Luc's ex-husband, Eric. Eric has escaped from an Orchard medical facility where he was injected with an experimental antibody that has killed all previous recipients in 48 hours.
The crew receives a radio transmission from a religious cult who plan to commit mass suicide by crashing into the sun. Luc falls under the unnatural influence of their leader, Brother Thirteen.
When a rival group of bounty hunters tries to steal the crew's prisoner, Percy is arrested for assaulting one of the bounty hunters, a member of the Oberon Militia. Rex, the leader of the rival group, uses Percy's arrest to blackmail Dante into freeing her brother, Goran, from the Nereid prison.
When a short circuit on the lower decks of the Tulip brings an unexplored section of the ship to life, Colonel Bramwell is released after 50 years in cryogenic sleep, believing Earth still is at war with the Raiders. Dante plans to use Bramwell's legendary status with the Raiders to find his son.
While on a shopping trip to find parts for the life support system in the Captain's Quarters, Dante is reunited with Marco, an old friend who was a rival for Penny's affections. Marco's business partner, Ike, works with the Raiders to locate special seeds that can grow in any climate. Percy begins to suspect Luc has a hidden agenda.
Every bounty hunter and law enforcement officer in the solar system seems to be after Harman, a former associate of Darius who may be the ""Rosetta Stone"" for the Divinity Cluster. Harman has developed superhuman speed, and refuses to talk to anyone but Darius. Dante's and Percy's suspicions of Luc come to a head when she helps Harman escape from The Tulip.
Darius pulls strings with Rudolpho to have the Tulip transport Arquette, an artist suspected of murder. The Orchard believes that Arquette's obsession with the large, swirling storm on Jupiter has given her extra-dimensional sight. Percy discovers they are being trailed by a cloaked ship that may be over three million years old.
Darius boards The Tulip to help Luc inform Dante about the Divinity Cluster.
When Rudolpho sells The Tulip to Max for conversion to a prison ship, Dante must infiltrate Max's organization, and fight off advances from Max's wife, Zelda.
While transporting a dangerous serial killer, The Tulip is diverted to search for survivors after an accident at a secret research station on Triton. When the ship is disabled by the station's graviton experiment, Dante stumbles on a time loop that gives him multiple chances to prevent Percy's death.
Caught in separate Bubble Universes, each member of the crew must outwit separate versions of their prisioner, insane serial killer Five.
Dante agrees to transport Rudolpho's friend, Stephen Hamilton, and his two daughters, unaware that Hamilton is being blackmailed by The Orchard to spy on Dante.
Dante is kidnapped by Tosca, an Orchard agent who plans to use Dante to find Travis, who she believes is the key to The Divinity Cluster. During the kidnapping, Caravaggio is infected with a virus that gives him a second, evil personality. The Tulip is boarded by Navarre, a rogue Orchard scientist who wants to help Luc rescue Dante. While Percy is trying to save the ship from self-destruction by Caravaggio, The Tulip is again boarded - this time by Salomea, a Raider who claims she is working for Travis.
The Tulip receives a cryptic massage from Percy that leads Dante to the special seeds that are concealed in her quarters. Dante bargains with the Raider leader, Senaca, to exchange the seeds for Percy and Travis (known to the Raiders as Zephryn). Travis reveals Penny's role in early experiments with The Divinity Cluster.
Tension and mistrust forms between the crew members as Travis becomes a reluctant member of The Tulip's crew. Dante discovers The Raiders' true intentions for the seeds, but is unsure how to intervene with The Tulip damaged in their escape from The Raiders. Luc is captured by Tosca who is assisting The Raiders with their mission. Eccelston returns from ""the dead"" with dire warnings about The Divinity Cluster.