Kirsten is recruited into a covert government agency to be 'stitched' into the minds of the recently deceased, using their memories to investigate murders and decipher mysteries that otherwise would have gone to the grave. Working alongside Kirsten is Cameron, a brilliant neuroscientist whose passion for the program is evident in his work. The secret program is headed by Maggie, a skilled veteran of covert operations, and includes Linus, a socially immature bioelectrical engineer and communications technician. Kirsten's roommate, Camille, a gifted computer science grad student, is also recruited to use her skills to assist Kirsten in her new role as a 'stitcher.'
Highly intelligent and emotionally distant, Kirsten Clark has an aptitude for technology but never expected that she’d be hacking into the minds of the recently deceased.
A dangerous new drug has claimed the life of a young woman and, while the Stitchers team is looking for its source, they run into Detective Fisher, who is on the same trail.
When a murky stitch doesn’t give enough evidence against a newlywed husband accused of killing his wife, Kirsten attempts to prove her strong feelings about his guilt. This effect on Kirsten, brought about by residual emotion from the stitch, makes Cameron worry that she will end up like Marta. Meanwhile, Linus and Camille get to know each other better.
When Cameron's neighbor is killed, the Stitchers group works to determine if the bullet was really meant for Cameron. As they stakeout the location from Cameron's apartment, Kirsten finds that she enjoys the reconnaissance, maybe a little too much. Meanwhile, Cameron shares more details with Kirsten about Marta's disastrous stitch.
When the algorithm for the Stitchers program turns up among thousands of classified documents hidden by a conspiracy theorist, Kirsten starts to suspect her colleagues. Meanwhile, Kirsten starts getting cryptic messages from an unexpected source.
The Stitchers team investigates a mysterious car accident that resulted in the death of a traumatic brain injury researcher. Meanwhile, Kirsten asks Linus for help deciphering a clue left by Ed Clark as she continues to question Maggie for more information on the origin of the Stitchers program.
Kirsten surprises the Stitchers team when they discover that she has a boyfriend, Liam, who shows up suddenly, prompting Maggie to covertly gather information on him. Meanwhile, a young woman's extravagant social life may be the clue to her death.
It’s Kirsten’s birthday and the Stitchers team is assigned to look into a disease researcher’s suicide. When the body begins showing signs that it is carrying a deadly virus, the whole lab is placed under quarantine. The team jumps to action as they search for a way out, racing against the clock as, one-by-one, they come down with symptoms of exposure.
The Stitchers team investigates the murder of an online psychic whose symbolic, layered memories are further complicated when Kristen sees the murder of another person in the stitch. Maggie expresses her reservations about Kirsten’s relationship with Liam. Meanwhile, Camille hesitantly agrees to meet Linus’s parents.
The Stitchers team is on the defence when Cameron and Detective Fisher are targeted in a shooting. Kirsten's stitch leads them to Robert Barbiero, a security expert who has worked with Maggie in the past and was close to Kirsten's mom. As Kirsten follows the clues that Ed Clark left her, she finds unexpected answers to long-held questions.
While Camille preps for her annual Halloween bash, the Stitchers team investigates the suicide of a young man, who may have abducted a missing college student. The stitch leaves Kirsten spooked, and she begins to worry she's being haunted by him as they race to find the missing girl.