Miami is a vacationer's paradise with its beautiful beaches, myriad of outdoor activities and sizzling nightlife. Yet, the city is situated in the center of a giant swamp making it a Garden of Eden for snakes and other overgrown reptiles - many not native to the area. Snakes are everywhere, and the potential for a snake to strike is at an all-time high. One hundred percent of backyards in Miami and throughout South Florida have snakes; you just can't always see them. Not to mention, dangerous alligators, aggressive iguanas and Africanized bees.
A families' escaped pet python kills their young daughter. Chuck searches the Everglades for a nasty Burmese python. Ernie must tear apart fences to capture an aggressive red tail boa loose in a suburban neighborhood.
An alligator blocking a roadway tries to rip off Lt. Lisa Wood's leg. A deadly rattlesnake strikes out from underneath thick brush, and when the Venom One team gets called out to a dog rescue, they find not one, but three killer snakes.