Brenda enters the high-stakes world of pharmaceutical research, when a drug trial for new anti-addiction medication lead to the death of one of the principal investigators. Nothing is quite as it seems as she investigates the high-powered president of the drug company sponsoring the trial, the seemingly easy-going psychiatrist and the teenaged participants in the study. Too soon, one of the teenagers falls victim to manipulation of the medication, and Brenda untangles a web of exploitation of the young victims leading to an unlikely criminal. Meanwhile, Flynn ratchets up his efforts to undermine Brenda's authority, first by going over her head to Pope, and then, when that fails, by unearthing a groundless ethics investigation Brenda faced in Atlanta. On the personal front, Brenda's relationship with Fritz heats up, much to Provenza's delight!