From TV Trope's entry on essential anime, meant to highlight trendsetting and defining works, those with of historical note, and major works of various genres. Targeted more for people who are first getting into anime and have literally no idea where to start or common conventions, sub genres, or tropes.
This is my own ranked and ordered list of the best/dankest anime that I've watched so far in my illustrious Chinese-cartoons-watching-career. If it's in the Top 50 (make it even Top 100), you better watch it ASAP because well... I do have phenomenal taste ( ͡° ͜ʖ ͡°)
More in-depth list is over at MAL http://myanimelist.net/profile/dankzel