You could see the conflict in his face as he tracked her running away, the decision that he just couldn't allow a witness this time, the pain afterwards. I suspect that that (piled atop everything else that'd just happened) is what broke his willingness to stay with the Syndicate (and to "do this any more") at all and pushed him to run.
Shout by SwissSennaVIP 2BlockedParent2021-12-14T20:25:35Z
I didn‘t think that Spike is a PoS, but after he shot the running kid: He definitely is.