Alien resembling aliens including the doctor of Ochanomizu and Higeyajiji emigrated from the stars that looked like the earth in emergency. However, the food crisis and humankind will begin attacking the aliens with cell shrink solution.
That priest was dying carving a single mark on the eyes of Christ decorated in the church. Apparently it seems to be a clue to teach the identity of the pirate who broke into the church. The same pirate begins to aim for beard hair that knew their secret.
Together with Dr. Jordan who ran away from under the president who plots world conquest, Atom who got into the underground tank fights the president. But the underground tank loses control and starts pushing towards the volcano.
Dogs transplanted their brains to the robot are remodeled by Dr. Ponkotsu and challenge humanity as a hot dog corps.
Disguising himself, as a human boy, Astro Boy goes undercover to investigate a drug trade. Some criminals have developed a drug called Yellow Horse, when injected it causes people to dance and make people want more. Professor Ochanomizu has been captured by the drug ring and injected. They try to blackmail him into helping them produce and distribute the drug in exchange for another shot. But Astro is able to pose as a Yellow Horse addict thanks to an artificial skin that makes it look like he is injecting it into himself. He tracks down the headquarters and leads the police to arrest them all. The Professor goes to rehab along with all the addicts for detoxification.
A robot, Pluto is built to kill the 7 strongest robots in the world, therefore making him the world's most powerful robot.
Pluto succeeds in disposing of Montblanc, North #2, Brando, Gesicht, Hercules, and Photar with ease, leaving Astro as his sole remaining target. After meeting Astro, he begins to question his actions.
Astro Boy and a group of passengers from a doomed rocketliner are stranded on an asteroid with strange characteristics and a mysterious monster.