Ryan has been accepted to NYU amid a whirlwind of change happening in the Peete Family. With only a few days before she leaves, Holly scrambles to plan a farewell party while figuring out how best to let go of her deceased father's ashes.
The Peetes are taking a road trip down memory lane: Holly and Matt are searching for the perfect place to bury their deceased father's ashes in his hometown of Philadelphia, and Dolores brings the family to Penllyn, PA, to show Roman the little village where she grew up.
Change is afoot for the Peete Boys when Holly and Rodney consider homeschooling Robinson and Roman. RJ thrives at his new job with the Dodgers as Holly struggles to adjust to his newfound independence. Meanwhile, Rodney is determined to help athletes suffering from the tragic brain disease CTE.
Worried about Ryan living in the big city, Holly starts to agonize over leaving Ryan at NYU without talking to her about boys and sexual consent. After a half-asked attempt to have the conversation with Ryan over FaceTime, Holly enlists Rodney's help to figure out a way to talk to her sons about the same subject.
Holly and Rodney support RJ as he attempts to achieve another milestone and pass his driver's permit test; Uncle Matt reveals his Parkinson's diagnosis to the family, inspiring Robinson to organize a HollyRod-junior style benefit concert.
After hearing about the police shooting of Charles Kinsey, a mental health therapist who was trying to help an autistic patient, Holly hosts a town hall discussion to bring together law enforcement and the special-needs community.
Two former officers give RJ and Robinson a crash course in police encounters; RJ shocks Holly and Rodney when he says that he is ready to move out; Dolores reveals a family secret and begins a search for a sister she hasn't seen in 57 years.
Holly and Dolores land a meeting with Sen. Kamala Harris to talk about how to reform police training; Robinson throws a hip-hop charity event for Uncle Matt; Dolores announces that she wants to move out.