Anthea pays one of London clinics a visit concerned that she's contracted HIV after a condom burst during a one-night stand.
Seventy-five-year old John attends to see if the bleeding from his penis is an infection he's caught after some risky activity in a nightclub or the return of prostate cancer.
Harry is worried that he's contracted HIV after a wild weekend clubbing. Kristian needs to have a wart removed because it's brought his sex life to a grinding halt.
And Stephano, already battling Hep C and HIV, discovers some new symptoms which he fears may be Gonorrhoea.
After a brief sexual encounter in a car park, Richard is shocked to find a strange spot on his penis and heads to the Birmingham clinic to get it checked out, but it turns out the spot isn't his biggest problem.
In London, Simon's been researching his symptoms on the internet and is worried he's caught anal herpes.
Luke visits the London clinic to see if a wild couple of months have put him at risk and is shocked by his results.
And porn star Eva May comes in to the clinic to hopefully get the all-clear so that she can return to work.
Jason wants to overcome the problems he has ejaculating, Jordan needs an STI test after a foursome, and Nu Nu is worried about recent unprotected sex
A stripper seeks a sexual health check-up. Newly bisexual Sophie needs tips on how to pleasure a woman. There's also advice on anal douching.
Emily requests an STI test to make sure her hook-up isn't cheating. Leticia seeks advice on bipolar and sex. And a male stripper has a rash down below.