Emmett Ryker's good friend, storekeeper John Conway (Jack Warden), is to marry a woman he met in San Francisco and has known for only a very short time, Rita Boland (Marilyn Erskine). When Rita comes to Medicine Bow, her relationship with John becomes strained because of her seeming unwillingness to consider having children. She turns to the bottle and it is clear she is haunted by some event in her past. Meanwhile, Emmett's past also threatens to catch up with him as two Garr brothers (John Milford and James Beck) whom he had sent to jail for a robbery attempt, and whose third brother he had killed in that same attempt, come seeking revenge. The two disconnected stories become intertwined, and then resolved, in a fateful showdown.
