Wow. SPOILER ALERT
The ending was brutal. What's more upsetting, it was real. I read other people's comments and there seems to be confusion over the ending. I don't see any room for confusion. Jackie’s end is common (albeit upsetting) for oxycodone addicts.
The ending was appropriate. They sold the story of fighting drug addiction all the way through. People die. Charlie. A marriage. A family. And no matter what side of any conflict J found herself upon, no matter how much good, or how much evil she unleashed into the world; it all came down to one line too many/too strong/too much. More heartbreaking, more engaging still is that her end is what faces countless people entangled in the nasty web of oxycodone addition. Not just then, but now, years after the show has ended. Every day the number of addicts grows, doctors and pill mills print prescriptions faster than people can fill them. Anyone who hasn't seen Dope Sick MUST SEE IT. There are ordinary people whose lives change if they suffer some banal injury. Their doctor has been assured by the pharma rep that oxy is non-addictive, so they prescribe it as standard for pain. We now know it is HIGHLY addictive, and when the injury heals and the prescriptions stop - what then? The damage is done. Many of those who can't access or afford oxy street prices turn to heroin. This is happening. May they all find peace.

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