Frank and Steve Smith are brothers who teach in the history department of a state university in China, Illinois. They also happen to be legends in their own minds who will often sacrifice facts, lessons and syllabi for the sake of being awesome.
Frank and Steve compete over their annual "Gentleman's Bet"; The Dean & The Mayor solicit Pony & Baby Cakes’ help for a Think Tank.
Frank's anus learns how to speak and becomes a world-famous stand-up comic.
Steve, Frank and Baby Cakes start a band in order to gain the attention of a beautiful celebrity.
Since crows have the intelligence of 4-year-old humans, the dean enrolls a murder of them as new students.
The Mayor bans eating anchovies in town; Trump's child is the newest student at UCI.
Baby Cakes cannot attend the faculty Parent's Day at UCI because he must visit his mother for the weekend.
In order to prove his masculinity, Frank challenges a boxing legend to a fight; Baby Cakes and Pony compete in a game of Dungeons & Dragons.
Steve, Frank, Baby Cakes and Pony all become life coaches for each other.
Steve and Baby Cakes strike it rich; Frank falls in love with a piece of a movie star.