Case File #34112: ""Dream House"" Blaine and Debbie McCallister summon the Office of Scientific Investigation and Research to investigate the cause of numerous strange occurrences at the site of their new home, after their teenage daughter is hospitalized as a result of a poltergeist encounter. Case File #52111: ""UFO Encounter"" Agents from the O.S.I.R. are summoned to a small town to investigate a double alien abduction of two boys and UFO sightings witnessed by many townspeople.
Case File #67102: ""Possession"" A software designer tells of demons attacking Case File #10103: ""Man Out of Time"" A disoriented man tells of being from the 17th century.
Case File #99101: ""Reptilian Revenge"" After an elderly man dies, his pet snakes escape Case File #44114: ""Ghostly Voices"" A voice calls a woman home.
Case File #77110: ""Creeping Darkness"" Impenetrable darkness threatens to engulf an Argentine town Case File # unknown: ""The Power"" Stress boosts a woman's psychokinesis.
Case File #47129: ""Free Fall"" A sky diver tells of defying gravity Case File #92109: ""The Presence"" A child fears a destructive force.
Case File #33130: ""The Infestation"" NASA scientists die searching for a meteorite Case File #87105: ""Human Apportation"" A Californian and her daughter inexplicably find themselves in Toronto.
Case File #28120: ""The Underneath"" A deadly creature lives in the sewers Case File #52113: ""Phantom Limb"" Strange events follow an accident that claimed a farmer's arm.
Case File #64131: ""The Transient"" A dybbuk invades the souls of innocents Case File #86126: ""Two Lost Old Men"" Young people pass through a forest's barren zone and instantly age 50 years.
Case File #623119: ""UFO Duplication"" Extraterrestrials clone farm inhabitants Case File #847117: ""Clara's Friend"" An apparition communicates with a girl.
Case File #702134: ""The Hunter"" A werewolf is suspected in cattle mutilations Case File #969121: ""The Healer"" Teen is credited with healing powers.
Case File #631136: ""The Curse"" Death strikes archaeologists who uncovered an Egyptian burial chamber Case File #260122: ""Angel on a Plane"" A mysterious woman safely lands a plane hit by lightning.
Case File #288128: ""Anasazi Cave"" Deaths at an archaeological dig may explain the mystery of the lost Anasazi Case File #199137: ""Devil's Triangle"" A man claims he was adrift in the Devil's Triangle.
Case File #763139: ""The Undead"" A homeless man revives during his autopsy and escapes Case File #569135: ""Stalker Moon"" A fan stalks an actress from the grave.
Case File #26014: ""Forbidden North"" A humanoid beast approaches a leg-trapped logger Case File #610115: ""Reincarnation"" A man undergoing past-life regression predicts the future.
Case File #213127: ""The Greenhouse Effect"" Plants attack a family Case File #213127: ""The Buzz"" Mysterious buzzing coincides with unexplained deaths.
Case File #206132: ""The Light"" As wounded Rollins lies near death, his evil doppelganger stalks the Office of Scientific Investigation and Research.
Case File #957176: ""The 13th Floor"" A possessed woman takes a horrible vengeance on her philandering husband Case File #284145: ""The Believer"" A kidnapper transmits his extortion demands psychically.
Case File #559146: ""The Fog"" A dense fog, mass hallucinations and a serial killer arrive simultaneously on death row Case File #810126: ""House on Garden Street"" An apparition appears to a couple under stress.
Case File #295143: ""Second Sight"" A kidney-transplant recipient has frightening visions Case File #734138: ""Chocolate Soldier"" A cult leader has power over women.
Case File #994124: ""The Fire Within"" Spontaneous human combustion Case File #232148: ""Fate"" A teen with psychic powers struggles to understand events leading to his best friend's death.
Case File #693142: ""Death at Sunset"" A mysterious illness claims its victims at sunset Case File #793144: ""Collision"" The soul of an accident victim possesses the driver who killed her.
Case File #321147: ""Perestroika"" The Office of Scientific Investigation and Research's Director of Operations Frank Elsinger orders Case Manager Doyle to lead a team of investigators to Archangelsk in Northern Russia. Having just viewed video footage of a team of Russian scientists examining a creature found frozen in a glacier by two gas plant caretakers, Elsinger does not reveal to Doyle that the last scene of the video showed scientist frightened and pleading for help.
Case File #262-201 After two electricians at work on a building suddenly disappear, along with a huge part of the construction, the Office of Scientific Investigation and Research arrives to investigate.
Case File #263-202 In a small farming community, the Office of Scientific Investigation and Research investigates the strange mutilation and seemingly ritualistic slaughter of livestock animals.
Case File #360-203 In swamp country, county doctor calls in the Office of Scientific Investigation and Research to help her find out why a teenager seems to be clinically dead but somehow alive.
Case File #245-208 The Office of Scientific Investigation and Research investigates several UFO reports in the industry area of Montex Bioengineering.
Case File #417-205 Deep in the interior of a national park, a strange epidemic strikes a Native American reserve, turning the residents into living statues.
Case File #567-212 After a blinding light explodes in a hospital room, a blood-covered entity throws the guard out into the hall and the body of a sixty-year-old woman, sentenced to life imprisonment for the murder of a police officer, disappears.
Case File #371-211 When a curator of a museum decapitated by an unknown assailant, the Office of Scientific Investigation and Research starts to investigate.
Case File #669-207 The Office of Scientific Investigation and Research is called to an abandoned industrial park to investigate a UFO sighting. Case Manager Matt Praeger hears a buzzing noise and disappears without a trace.
Case File #267-210 When a corporal investigates an onslaught of light and noise, disappearing with a scream of pain and horror, the Office of Scientific Investigation and Research starts to investigate.
Case File # 905-209 When the pool water mysteriously starts to churn and boil, a man drowns and sinks to the bottom. The Office of Scientific Investigation and Research starts to investigate.
Case File # 416-209 The Dean at Braddock University brings the Office of Scientific Investigation and Research in to investigate an incident involving psychokinetic power.
Case File #350-213 The Office of Scientific Investigation and Research is called in to help locate a missing police officer.
Case File #340-212 After a woman, recovering in her hospital bed from knee surgery, suddenly cries out from a terrifying dream and bleeds spontaneously from deep wounds, the Office of Scientific Investigation and Research arrives to secure the building following the inexplicable occurrence.
Case File #936-214 Case Manager Matt Praeger brings in the Office of Scientific Investigation and Research team to help his old friend David Vancha save the life of his wife Zoe.
Case File #604-215 Hotel-owner Clifford Ashe calls in the Office of Scientific Investigation and Research to investigate the haunting of the Ashe Plaza Hotel.
Case File #938-216 A dealer of rare animals breaks into an abandoned factory with an accomplice, who afterwards is pulled back into the complex by some unseen presence.
Case File #309-217 When a city worker is killed by a wave of light and sound, the Office of Scientific Investigation and Research is called in to investigate.
Case File #721-219 When a horrific murder takes place, the Office of Scientific Investigation and Research gets a call to come to a gallery where they find a body strung from the ceiling in the back room, his clothing shredded and his eyes ground into their sockets.
Case File #721-219 The Office of Scientific Investigation and Research investigates a suburban home in which the living room has become an icy chamber.
Case File #420-202 Case Manager Matt Praeger flies to Halifax to bail out Michael Kelly, who has been arrested for being drunk and disorderly.
Case File #104-723 When a huge beast charges out of the woods and rips man's limb, a local police calls in the Office of Scientific Investigation and Research to identify the attacker.
Case File #102-964 Ray Donahue and Peter Axon fan out through a secret research facility searching for Axon's friend Dr. Leon Schraft, a colleague from Axon's MIT days.
Case File #898750 As the third season begins, physicist Peter Axon is the only remaining member of the Office of Scientific Investigation and Research team. Dr. Anton Hendricks is apparently dead, having disappeared into a mysterious apportation device known as the Arch, case manager Matt Praeger has tendered his resignation after differences with the O.S.I.R.'s Director of Operations Frank Elsinger and senior data analyst Lindsay Donner has left the team after running afoul of Praeger and revealing confidential information. Axon and Curtis Rollins, the case manager assigned to the Arch case, take their investigation to a remote area of northern Quebec after an RCMP officer finds a woman wandering alone in the sub-tundra. It turns out the woman had vanished into the Arch and then re-appeared 2,000 miles away. Lindsay Donner and Matt Praeger rejoin the team to recover Hendricks from the Arch.
Case File #751718 Following a memorial service for Dr. Anton Hendricks the Office of Scientific Investigation and Research team members receive an anonymous phone call informing them that Hendricks is at a nearby hospital unconscious and on a ventilator.
Case File #898777 When a forest area turns into a bone-dry wasteland virtually overnight, a government agriculture official turns to the Office of Scientific Investigation and Research for help.
Case File #145345 The Office of Scientific Investigation and Research is called into action when the mutilated corpse of a police detective who gunned down an escaped convict is found in a dumpster.
Case File #569-977 The Office of Scientific Investigation and Research case manager Matt Praeger is institutionalized after a case goes tragically wrong. Working undercover as an arms dealer in order to gain access to a teenager with ESP Praeger gets caught in the middle of a double cross and apparently fires the bullet that kills the youth.
Case File #659-311 The Office of Scientific Investigation and Research case manager Matt Praeger, security co-ordinator Ray Donahue, chief science analyst Peter Axon and senior data analyst Lindsay Donner visit the scene of a grisly, pre-Halloween murder of two college students who died after having their faces torn off.
Case File #600-001 The Office of Scientific Investigation and Research investigates after the body of an elderly woman is found in the basement of a soon-to-be demolished apartment building.
Case File #965-789 Dr. Anton Hendricks' wife has recently returned from a mysterious apportation device called the Arch, into which she vanished 12 years ago. Hendricks has become increasingly suspicious that she is not the Catherine he knew.
Case File #828-456 The Office of Scientific Investigation and Research investigates the unusual death of a large South American rodent called a capybara at the Windsor Animal Hospice.
Case File #790-002 Matt Praeger's daughter, Dana, is sleeping over at the country home of her friend, Vanessa, when the girls hear a strange noise coming from the bedroom of Vanessa's adopted brother. The Office of Scientific Investigation and Research team arrives at the house to conduct an ""unofficial"" investigation.
Case File #340-872 Archaeologist and former lover of Lindsay Donner finds a 13th century burial shroud inside an ancient Druid coffin. At his request, Donner and the Office of Scientific Investigation and Research team join him in London to verify the authenticity of the ""winding cloth"" and identify the man buried in it.
Case File #500-208 A senior data analyst of the Office of Scientific Investigation and Research dies of an apparent heart attack at a Cuban-style neighborhood party. The rabbi who's conducting the funeral suddenly hears scratching sounds coming from coffin, opens the lid and finds out the man is alive.
Case File #226-051 The Office of Scientific Investigation and Research senior data analyst Lindsay Donner and pathologist Claire Davison are called to the Newgate Correctional Facility after an inmate dies mysteriously while in solitary confinement.
Case File #443-987 Alone on Valentine's Day, Lindsay Donner visits a neighborhood after-hours club, where she catches the attention of the bartender. Despite the attraction Donner leaves and is called back to the vicinity the following morning when a body is found in the alley.
Case File #392-101 Tessler Industries, a video-game giant, is testing one of its new virtual-reality war games at the Office of Scientific Investigation and Research Central Lab. When a woman is knocked to the floor with a very real head wound, Elsinger calls for the O.S.I.R. team to investigate.
Case File #222-989 The Office of Scientific Investigation and Research investigates after a UFO is sighted in the woods near the private community of Poplar Glen.
Case File #333-016 The Office of Scientific Investigation and Research team investigates after an auto shop teacher at Royalton Custodial School is crushed against a wall by a car. The ""accident"" could be the work of a student with telekinetic ability.
Case File #009-873 Two computer programmers trying to develop a solution to the Y2K problem enter a sealed lab and begin work. Later, they go into convulsions and, with blood pouring from their eyes and ears, fall to the ground dead. The Office of Scientific Investigation and Research team arrives at the lab to investigate.
Case File #899-997 The Office of Scientific Investigation and Research is transporting a young woman who's had an alien encounter, when their van is engulfed in a bright light from a UFO, temporarily blinding the investigator, and the woman disappears.
Case File #098-509 Peter Axon and Frank Elsinger run tests on an electromagnetic field (EMF) laser cannon in the lab at Tessler Industries to destroy a missile guidance system. After the experiment fails when the laser device overheats, a janitor resets the cannon and destroys the missile guidance system.
Case File #298-321 Psychic healer has just successfully restored the sight of a blind woman when he is interrupted by the Office of Scientific Investigation and Research agents and taken to the central lab to test the man's healing powers.
Case File #298-321 Peter Axon is working on a secret project for the Office of Scientific Investigation and Research head Frank Elsinger that seems to have special and very personal significance for Elsinger, who assigns case manager Curtis Rollins to provide security for Axon as he finishes the project, which involves mapping out an anonymous individual's genetic code.
Case File # unknown Struck by lightning, a woman must release the electricity through sex in order to survive.
Case File # unknown The O.S.I.R. investigates satanic cult activity on a college campus.
Case File # unknown Matt inadvertently enters an alternate dimension as a contestant on a game show where he must re-examine his life.
Case File # unknown The O.S.I.R. investigates a plane crash and its survivors, who have been in a sort of limbo since their disappearance 10 years ago.
Case File # unknown A doctor's mission to colonize a new world forces Matt to make a decision about his future.
Case File # unknown An old man following three Old West outlaws is actually Axon 30 years in the future, warning his younger self against inventing time-travel.
Case File # unknown The team's investigation of a woman's precognition of her own death leads to a shocking discovery.
Case File # unknown A spiritual entity is blamed for an outbreak of murders at a Hollywood retreat.
Case File # unknown Axon must race against time to save the life of an alien grounded in a meteor crash.
Case File # unknown Donner and Stone are caught in a sinister plot when they investigate a rave club overrun by zombies.
Case File # unknown A journalist's relationship with a Death Row inmate causes a rare haunting.
Case File # unknown An autistic boy develops psychokinetic abilities while mourning the death of his twin brother.
Case File # unknown Mysterious sky-falls may be the result of the Super Sargasso Sea theory.
Case File # unknown A ghost-like image in a photograph might be the link between a serial killer and a real-life angel.
Case File # unknown Oil drilling in an ancient tribal burial ground unleashes a demon killer.
Case File # unknown Peter's old friend lures him into the wilderness seeking retribution for past deeds.
Case File # unknown An angry spirit torments a group of artists in an old church.
Connor Doyle, the team's case manager in the first season comes back from the dead, but this time his intentions are not all good.
Case File # unknown During a search for three missing operatives, the O.S.I.R. uncovers a gruesome situation, cannibalism.
Case File # unknown During an investigation, Donner, Stone and Davison are trapped in an elevator.
Case File # unknown Lindsay and Peter are under cover as a married couple to investigate aberrant behavior among community residents.