In the fourth series the residents of Manchester's most outrageous estate have two new cops to contend with. But the Gallaghers don't need to worry now they've teamed up with the Maguires. Especially when, after a stint in prison, prodigal son Jamie Maguire arrives to set sparks flying with Karen. Then there are his brothers, the not-so-bright Shane and Micky, a wannabe hard-man struggling with his own secrets. Frank and the kids are sent into a spin when mum Monica turns up, claiming to be back for good. Lip is taking his parental responsibilities seriously until thoughts of university offer him the escape he's always wanted. Carol is back but still having trouble keeping her legs and mouth shut, while Kash is happy screwing the council. And what is the connection between Kev, Veronica, Marty, Sue and a Romanian baby?
The Gallaghers' return for a fourth series, and its Lip's 18th birthday but not all is going to be clean sailing as there’s a few surprises ready to hit him. First the Maguires expect him to do something for them. But the biggest shock of all is his long-lost mother Monica turning up out of the blue with a bombshell that could turn their lives upside down.
Frank’s desperate to keep the fact that he’s still married to estranged wife Monica from Sheila, and Monica’s not making it easy for him. But Sheila can see that she has competition for Frank and sets about trying to reunite Monica with her estranged lesbian lover. But is Monica still a lesbian?
Monica manages to seduce Frank and sink her claws back in, but he dare not tell Sheila that he and Monica have been sleeping together. Sheila proves to be a frightening adversary when scorned and Frank could be in real danger. But neither Sheila nor Monica want to share him and he has to decide on which wife he wants. But who will he choose?
Ian gets more than he bargained for when a new person enters his life. Another death in the Maguire household causes Mimi to think the family may be cursed.
Debbie's glad to have her dad back at home, but Monica's not happy with all the attention Frank is giving her and tells her it's time she found herself a boyfriend. Also Ian catches the eye of someone he least expected.
Carl wants his family back together and that means getting rid of Norma - for good. Unfortunately, things don't go to plan when Norma proves to be a very tough adversary. Frank agrees to work on Shane's ice cream van - the Maguires use it as a cover for dealing and Frank's got E's on tap! However, there's trouble brewing.
Explosions across the estate spark fears that Chatsworth is a terrorist target. But it has the Maguire's worried that they're under threat from folk a little closer to home when Patrick finds the family semtex missing. Meanwhile when Frank reveals to Monica she was never his first choice over Sheila, Monica vents her anger by turning to Norma for gifts and goodies.